| Company Name: |
AstaTech (Chengdu) Pharma. Co., Ltd.
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| Tel: |
15928766785 15928766785 |
| Email: |
wupengcheng@astatech.cn |
| Products Intro: |
Product Name:3-hydroxy-2-phenylquinoline-4-carboxylic acid
CAS:485-89-2
Purity:0.95 Package:5G;25G;100G;250G
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| | oxycinchophen Basic information |
| Product Name: | oxycinchophen | | Synonyms: | oxycinchophen;Fenidrone;Magnofenyl;Magnophenyl;Oxinofen;4-Quinolinecarboxylic acid, 3-hydroxy-2-phenyl-;Oxicinchophen;Chinoxone | | CAS: | 485-89-2 | | MF: | C16H11NO3 | | MW: | 265.26 | | EINECS: | 2076244 | | Product Categories: | | | Mol File: | 485-89-2.mol |  |
| | oxycinchophen Chemical Properties |
| Melting point | 206.5°C (rough estimate) | | Boiling point | 408.48°C (rough estimate) | | density | 1.1861 (rough estimate) | | refractive index | 1.5300 (estimate) | | storage temp. | 2-8°C | | pka | 0.55±0.10(Predicted) | | color | Minute, deep yellow prisms from alc |
| Toxicity | LD50 orl-dog: >5 mg/kg PEMNDP 9,643,91 |
| | oxycinchophen Usage And Synthesis |
| Uses | Oxicinchophen has bene used to study P-selectin antagonistic activity, DHOD inhibitory activity, SAR of quinoline salicylic acids using Pfitzinger reaction of isatin derivatives with (acetyloxy)acetophenone derivatives; effect of antiinflammatory drugs on vascular smooth muscle; increase in oxygen consumption in the absence of a phosphate acceptor and to inhibit ATP synthesis in the isolated rat liver mitochondria. | | Definition | ChEBI: Oxycinchophen is a member of quinolines. | | Safety Profile | Low toxicity by ingestion and skin contact. When heated to decomposition it emits toxic fumes of NOx. | | Purification Methods | It is precipitated from alkaline solution on acidification and crystallises from EtOH or AcOH in yellow crystals. [Marshall & Blanchard J Pharmacol 95 186 1949, Beilstein 22 H 245, 22 II 183, 22 III/IV 2383.] |
| | oxycinchophen Preparation Products And Raw materials |
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