estriol succinate

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Products Intro: CAS:514-68-1
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Products Intro: Product Name:estriol succinate
CAS:514-68-1
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Products Intro: Product Name:Estriol Succinate
CAS:514-68-1
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estriol succinate Basic information
Product Name:estriol succinate
Synonyms:Estra-1,3,5(10)-triene-3,16α,17β-triol 16,17-bis(hydrogen succinate);113-22-4 (Di-hydrochloride salt);Einecs 208-185-1;Estrioli succinas;Estrioli succinas [inn-latin];Estriolo succinato;Estriolo succinato [dcit];Oestriol succinate
CAS:514-68-1
MF:C26H32O9
MW:488.53
EINECS:208-185-1
Product Categories:
Mol File:514-68-1.mol
estriol succinate Structure
estriol succinate Chemical Properties
Boiling point 716.8±60.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
pka4.40±0.17(Predicted)
Safety Information
MSDS Information
estriol succinate Usage And Synthesis
OriginatorHemostyptanon,Endopancrine,France,1966
UsesEstrogen.
DefinitionChEBI: Estriol succinate is a steroid ester and a hemisuccinate.
Manufacturing ProcessSuccinic anhydride and 60 ml of pyridine is heated at 90°C for 4 hours, after which the reaction mixture is poured into water. The aqueous solution is extracted with ether, the ether layer is separated, washed with diluted sulfuric acid and after that with water until neutral, then evaporated to dryness to obtain 14 grams of an amorphous substance. Melting point 82° to 86°C. This drying residue proves to consist of a mixture of estriol disuccinate and estriol monosuccinate, which are separated by repeated crystallization from a mixture of methanol and water.
Brand nameTheelol (Parke-Davis).
Therapeutic FunctionEstrogen
estriol succinate Preparation Products And Raw materials
Raw materialsSuccinic anhydride-->Estriol
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