Company Name: |
Dodhia Group
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Tel: |
+91-9619867345 +91-9619867345 |
Email: |
jinesh@dodhiagroup.com |
Products Intro: |
Product Name:Ciclonicate Purity:99% Package:1 kg,5 kg, 10 kg,25kg
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:Ciclonicate CAS:53449-58-4 Purity:0 Package:1mg
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Company Name: |
Leancare Ltd.
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Tel: |
+33 962096793 |
Email: |
enquiry@leancare.co.uk |
Products Intro: |
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| ciclonicate Basic information |
Product Name: | ciclonicate | Synonyms: | ciclonicate;Bled;Cortofludan;Cyclonicate;rel-3-Pyridinecarboxylic acid (1S*)-3,3,5β*-trimethylcyclohexane-1α*-yl ester;3-Pyridinecarboxylic acid, (1R,5S)-3,3,5-trimethylcyclohexyl ester, rel-;Elastan;P-350 | CAS: | 53449-58-4 | MF: | C15H21NO2 | MW: | 247.336 | EINECS: | 2585614 | Product Categories: | | Mol File: | 53449-58-4.mol | |
| ciclonicate Chemical Properties |
Melting point | <25 °C | Boiling point | bp0.6 127-128° | density | 1.06±0.1 g/cm3(Predicted) | pka | 3.14±0.10(Predicted) |
| ciclonicate Usage And Synthesis |
Originator | Bled, Poli, Italy ,1978 | Definition | ChEBI: Ciclonicate is an aromatic carboxylic acid and a member of pyridines. | Manufacturing Process | To a solution of 142 g (1 mol) of trans-3,3,5-trimethylcyclohexanol in 400 cc
of anhydrous benzene heated to 70 C is added gradually 178 g (1 mol) of
niacin chloride hydrochloride. Heating is carried out under reflux conditions for
3 hours, the solution is cooled, the ester hydrochloride is filtered off and then
recrystallized in an ethanol-ethyl ether mixture to obtain 227 g (80% yield) of
product melting at 155°C to 157°C. By treating the hydrochloride with an aqueous solution of NaOH at 0°C, the
free base is obtained in the form of a viscous white liquid which boils at 115°C
under 0.05 mm. | Therapeutic Function | Vasodilator |
| ciclonicate Preparation Products And Raw materials |
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