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4-Morpholineethanesulfonic acid

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Company Name: Yunbio Tech Co.,Ltd.
Tel: 010-60605551
Email: yunbiochem@126.com
Products Intro: Product Name:MES
CAS:4432-31-9
Purity:98% Package:10g;100g;500g;1kg;5kg;10kg,100kg,1ton Remarks:Buffer
Company Name: Tangshan Moneide Trading Co., Ltd.
Tel: 86-315-8309571 15633399667
Email: sales@moneidechem.com
Products Intro: Product Name:MES
CAS:4432-31-9
Package:500g;1kg;25kg
Company Name: Qingdao Xinfeng Biological Technology Co., Ltd
Tel: 13969668515
Email: yan@songfon.com
Products Intro: Product Name:2-Morpholinoethanesulfonic Acid
CAS:4432-31-9
Purity:99.9 Package:1ASSAYS;0.1USD
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Email: info@dakenchem.com
Products Intro: Product Name:4-Morpholineethanesulfonic acid
CAS:4432-31-9
Purity:99% Package:100g ,1KG ,5KG 25KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:4432-31-9
CAS:4432-31-9
Purity:0.99 Package:25KG,5KG;1KG;500G

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4-Morpholineethanesulfonic acid Chemical Properties
Melting point >300 °C(lit.)
Boiling point 102°C
density 1.208 (estimate)
refractive index 1.5500 (estimate)
storage temp. 2-8°C
solubility H2O: 0.5 M at 20 °C, clear
form Powder
pkapKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011
color White
PH2.5-4.0 (25℃ in neat)
PH Range5.5 - 6.7
λmaxλ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck 13,5929
BRN 6350956
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeySXGZJKUKBWWHRA-UHFFFAOYSA-N
CAS DataBase Reference4432-31-9(CAS DataBase Reference)
EPA Substance Registry System4-Morpholineethanesulfonic acid (4432-31-9)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25-22
WGK Germany 1
RTECS QE9104530
HS Code 29349990
MSDS Information
ProviderLanguage
2-(N-Morpholino)ethanesulfonic acid English
SigmaAldrich English
4-Morpholineethanesulfonic acid Usage And Synthesis
Application

4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.

Chemical PropertiesWhite/clear crystalline powder
UsesBiological buffer.
Uses
MES solution has been used to activate microspheres. It has also been used as a component of activating solution to activate carboxyl groups of poly lactic-co-glycolic acid (PLGA).
General Description
MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.
Purification MethodsCrystallise MES from hot EtOH containing a little water. The picrate crystallises from EtOH and has m 178.8-182o. [Malkiel & Mason J Org Chem 8 199 1943, Beilstein 27 III/IV 370.]
4-Morpholineethanesulfonic acid Preparation Products And Raw materials
Raw materialsSodium sulfite-->Sodium hypochlorite-->Sulfur trioxide-->LARD-->METHYL LAURATE-->Methyl palmitate
Tag:4-Morpholineethanesulfonic acid(4432-31-9) Related Product Information
0.1 M MES PH 6.0 - 20% PEG 6000 SOLUTION 2-(N-MORPHOLINO) ETHANESULFONIC ACID,MONOHYDRATE (MES) MES MONOHYDRATE BUFFER GRADE AMBERLITE CG-50 (100-200 MES 3-(N-MORPHOLINO)ETHANE SULFONIC ACID (MES) AMMONIUM SULFATE 0.2M-MES PH 6.5; 0.1M-& 0.1 M MES PH 6.0 - 20% PEG 600 SOLUTION 2-methylthioadenosine-5’-o-diphosphate(2-mes-atp),sodiumsal H-Gln(Trt)-2-chlorotrityl PS resin, 1% DVB (200-400 mes 28% SP-1700 ON CHROMOSORB PAW 80/100 MES H, 20G 4-Morpholineethanesulfonic acid monohydrate, MES-d13,MES-d13,4-Morpholineethanesulfonic acid monohydrate, MES-d13 MES-K,MES POTASSIUM SALT,2-(N-Morpholino)ethanesulfonic acid potassium salt, 4-Morpholineethanesulfonic acid potassium salt 4-Morpholineethanesulfonic acid flumorph MesBuffer Ethanesulfonic acid Ascoric Acid Moroxydine