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FASUDIL

FASUDIL Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: Product Name:103745-39-7
CAS:103745-39-7
Purity:0.99 Package:25KG,5KG;1KG;500G
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:5-(azepan-4-ylsulfonyl)isoquinoline dihydrochloride
CAS:103745-39-7
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name: FASUDIL
CAS: 103745-39-7
Purity:99% Package:1KG;7USD
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Email: linda@hubeijusheng.com
Products Intro: Product Name:FASUDIL
CAS:103745-39-7
Purity:0.99 Package:5KG;1KG
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:FASUDIL
CAS:103745-39-7
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg

Lastest Price from FASUDIL manufacturers

  • FASUDIL
  • US $7.00 / KG
  • 2019-07-06
  • CAS: 103745-39-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1000KG
FASUDIL Basic information
Product Name:FASUDIL
Synonyms:Fasudil HCI;FASUDIL;1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE;at877;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-4-diazepine;HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE;HA 1077, DIHYDROCHLORIDE, 99+%;Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
CAS:103745-39-7
MF:C14H17N3O2S
MW:291.37
EINECS:816-154-4
Product Categories:Protein Kinase Inhibitors and Activators;Protein Kinase;Signalling;Angiogenesis and Metastasis;Intracellular signaling;APIs;Fasudil ada@tuskwei.com sky;18031153937@189.cn;Glutaraldehyde ada@tuskwei.com whatsapp;8618031153937;ERIL
Mol File:103745-39-7.mol
FASUDIL Structure
FASUDIL Chemical Properties
Boiling point 506.2±60.0 °C(Predicted)
density 1.289±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility H2O: >200 mg/mL
form solid
pka9.73±0.20(Predicted)
color white
Water Solubility Soluble in water or DMSO
CAS DataBase Reference103745-39-7(CAS DataBase Reference)
Safety Information
WGK Germany 3
RTECS HM4031166
HS Code 29334900
MSDS Information
FASUDIL Usage And Synthesis
Chemical PropertiesWhite Crystalline Solid
Usesvasodilator (cerebral), Ca antagonist
UsesA potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced co ntraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho- associated Kinase (ROCK IC50= 10.7 uM).
Biological ActivityCyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Ca2+ antagonist and vasodilator. Also inhibits proliferation of vascular smooth muscle cells.
FASUDIL Preparation Products And Raw materials
Raw materialsIsoquinoline
Tag:FASUDIL(103745-39-7) Related Product Information
5-Quinolinesulfonic acid, 2-methyl- CINITAPRIDE HYDROGEN TARTRATE Fosaprepitant dimeglumine CAL-101 Temsirolimus Rapamycin Ripasudil Icotinib Radotinib Oxiracetam Nimodipine HA1077 (Fasudil) 1-(5-Isoquinolinylsulfonyl)homopiperazine dihydrochloride, Fasudil dihydrochloride Fasudil Monohydrochloride,FASUDIL HCL,FASUDIL HYDROCHLORIDE,FASUDIL DIHYDROCHLORIDE H-1152Glycyl, Dihydrochloride FASUDIL 1-[(1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL)SULFONYL]HEXAHYDRO-1H-1,4-DIAZEPINE (S)-(+)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLYNYL)SULFONYL]HOMOPIPERAZINE