| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:Elevenostat
CAS:1454902-97-6
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
| Email: |
sales@dcchemicals.com |
| Products Intro: |
Product Name:Elevenostat
CAS:1454902-97-6
Purity:98% HPLC Package:100mg，250mg，1g
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| Company Name: |
Jingmo (Xiamen) Biotechnology Co., Ltd
|
| Tel: |
13621943973 13515979683 |
| Email: |
sales@jamxmpharmatech.com |
| Products Intro: |
Product Name:N-hydroxy-4-((3-(2-methoxyphenyl)ureido)methyl)benzamide
CAS:1454902-97-6
Purity:96% Package:1g;5g;10g
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| | Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Basic information |
| | Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Chemical Properties |
| density | 1.328±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (792.85 mM; Need ultrasonic) | | pka | 8.92±0.10(Predicted) |
| | Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Usage And Synthesis |
| Biological Activity | Elevenostat (JB3-22) is a selective HDAC11 inhibitor (IC50=0.235 μM). Anti-multiple myeloma (MM) activity[1]. | | References | [1]. Huang J, et al. Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Sci Rep. 2017;7(1):8626. Published 2017 Aug 17.
[2]. Mostofa A, et al. Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma. JCI Insight. 2021;6(24):e151713. Published 2021 Dec 22. |
| | Benzamide, N-hydroxy-4-[[[[(2-methoxyphenyl)amino]carbonyl]amino]methyl]- Preparation Products And Raw materials |
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