| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
13675144456 |
| Email: |
alan.chow@synzest.com |
| Products Intro: |
Product Name:N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri
din-4-yl)benzoyl]piperidine-3-carboxamide
CAS:1922098-90-5
Purity:95% HPLC Package:1g;5g;10g;
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:CCG-257081
CAS:1922098-90-5
Purity:99.00% Package:1mg;5mg;10mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CCG-257081
CAS:1922098-90-5
Purity:99.92% Package:1mg/RMB 1280;5mg/RMB 3190;10mg/RMB 4670
|
|
| | N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri
din-4-yl)benzoyl]piperidine-3-carboxamide Basic information |
| | N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri
din-4-yl)benzoyl]piperidine-3-carboxamide Chemical Properties |
| Boiling point | 689.1±55.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | pka | 13.69±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri
din-4-yl)benzoyl]piperidine-3-carboxamide Usage And Synthesis |
| Description | CCG-257081 is an inihibitor of Rho/MRTF/SRF pathway. CCG-257081 has shown efficacy in preventing bleomycin-induced fibrosis in several mouse models. | | Uses | MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis[1]. | | References | [1] Larsen Scott D, et al. Preparation of substituted piperidine-3-carboxamides as inhibitors of myocardin-related transcription factor and serum response factor (MTRF/SRF)-mediated gene transcription. World Intellectual Property Organization, WO2016073847 A2. 2016-05-12. |
| | N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri
din-4-yl)benzoyl]piperidine-3-carboxamide Preparation Products And Raw materials |
|