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5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione

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5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Suppliers list
Company Name: Shanghai Daken Advanced Materials Co.,Ltd
Tel: +86-371-66670886
Email: info@dakenam.com
Products Intro: Product Name:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS:764667-64-3
Purity:99% Package:100g ;1KG ;5KG 25KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione 764667-64-3
CAS:764667-64-3
Purity:99% Package:25KG;5KG;1KG
Company Name: Anqing Chico Pharmaceutical Co., Ltd.
Tel: 15380796838
Email: chloewu@chicopharm.cn
Products Intro: Product Name:5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS:764667-64-3
Purity:98% Package:10g;100g;1kg; 25kg or More
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS: 764667-64-3
Purity:99% Package:1KG;7USD
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Sitagliptin Impurity 96
CAS:764667-64-3
Purity:0.99 Package:10mg;25mg;50mg;100mg

5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione manufacturers
5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Basic information
Product Name:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione
Synonyms:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione;5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-1,3-dioxane-4,6-dion;5-[1-hydroxy-2-92,4,5-trifluorophenyl0ethylidene]-2,2-dimethyl;1,3-Dioxane-4,6-dione,5-[1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-diMethyl-;5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)-4,6-dionethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione;5-(1-Hydroxy-2-(2,4,5-trifluorophenyl);ethylidene);Sitagliptin Impurity 96
CAS:764667-64-3
MF:C14H11F3O5
MW:316.23
EINECS:
Product Categories:Aromatics;Heterocycles;Impurities;Intermediates
Mol File:764667-64-3.mol
5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Structure
5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Chemical Properties
Melting point 117 °C (decomp)
Boiling point 489.0±45.0 °C(Predicted)
density 1.462±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka4.50±1.00(Predicted)
color White to Off-White
Safety Information
MSDS Information
5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Usage And Synthesis
Chemical PropertiesWhite to Off-white Solid.
Uses5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).
Application5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene] is an intermediate for the synthesis of sitagliptin. Sitagliptin is a new type of anti-type II diabetes drug approved by the FDA and the first dipeptidyl peptidase-IV inhibitor drug for the treatment of type II diabetes.
5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione Preparation Products And Raw materials
Preparation ProductsMethyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate-->(Z)-Methyl 3-aMino-4-(2,4,5-trifluorophenyl)but-2-enoate-->Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)-
Tag:5-1-hydroxy-2-(2,4,5-trifluorophenyl)ethylidene-2,2-dimethyl-1,3-dioxane-4,6-dione(764667-64-3) Related Product Information
Sitagliptin Impurity 28 Sitagliptin Impurity 46 Sitagliptin Impurity 77 Sitagliptin impurity 5 Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate 2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Sitagliptin Impurity 34 2,4,5-TRIFLUOROBENZYL CHLORIDE (R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)- Sitagliptin Sitagliptin Impurity 14 Sitagliptin Defuoro IMpurity 5 Sitagliptin DeaMino IMpurity 1 (S)-Sitagliptin Phosphate 2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE (R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione