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| | osthenol Basic information |
| Product Name: | osthenol | | Synonyms: | 7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one;7-Hydroxy-8-isopentenyl-2H-1-benzopyran-2-one;7-Hydroxy-8-prenylcoumarin;NSC 625328;2H-1-Benzopyran-2-one, 7-hydroxy-8-(3-methyl-2-buten-1-yl)-;inhibit,selective,Monoamine Oxidase,MAO,depression,competitive,Osthenol,Inhibitor,coumarin,Ostenol | | CAS: | 484-14-0 | | MF: | C14H14O3 | | MW: | 230.26 | | EINECS: | | | Product Categories: | | | Mol File: | 484-14-0.mol |  |
| | osthenol Chemical Properties |
| Melting point | 89-91 °C | | Boiling point | 422.8±45.0 °C(Predicted) | | density | 1.203±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 8.45±0.20(Predicted) | | LogP | 3.342 (est) |
| | osthenol Usage And Synthesis |
| Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Rhizoma et Radix Notopterygii. | | Definition | ChEBI: Osthenol is a hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group. It has a role as a plant metabolite and an antifungal agent. It is functionally related to an umbelliferone. | | Biological Activity | Ostenol (Ostenol), a preacylated coumarin isolated from the dried roots of Ostonia, is a reversible, selective and competitive inhibitor of human monoamine oxidase-A (hMAO-A) (Ki=0.26 μM) . Oshenol has a potential selective inhibitory effect on recombinant hMAO-A with IC50 of 0.74 μM, showing a high selectivity index for hMAO-A and hMAO-B. |
| | osthenol Preparation Products And Raw materials |
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