| Company Name: |
Guangzhou Ribobio Co.,LTD Gold
|
| Tel: |
020-82119435 18922123670 |
| Email: |
marketing@ribobio.com |
| Products Intro: |
Product Name:CpG 1018
Purity:standard; HPLC; PAGE Package:20nmol; 50nmol; 100nmol; 1g; 10g; 1kg; 10kg
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| Company Name: |
Apextide Co Ltd Gold
|
| Tel: |
15300650552 |
| Email: |
info@apextide.com |
| Products Intro: |
Product Name:CpG1018
Purity:>=95.0% Package:10mg;1g;10g;100g
|
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| | CpG1018 Basic information |
| Product Name: | CpG1018 | | Synonyms: | ODN 1018;CpG1018;5' TGA CTG TGA ACG TTC GAG ATG A 3' | | CAS: | 937402-51-2 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CpG1018 Structure]() |
| | CpG1018 Chemical Properties |
| form | Solid | | color | White to off-white |
| | CpG1018 Usage And Synthesis |
| Uses | ODN 1018 (1018 ISS), an oligodeoxynucleotide, is a TLR-9 agonist. ODN 1018 is also a synthetic immunostimulatory sequence that can be used as vaccine adjuvant. Sequence: 5′-TGACTGTGAACGTTCGAGATGA-3′[1][2]. | | IC 50 | TLR9 | | References | [1] Friedberg JW, et al. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. Br J Haematol. 2009 Aug;146(3):282-91. DOI:10.1111/j.1365-2141.2009.07773.x
[2] Eng NF, et al. The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAV? review. Hum Vaccin Immunother. 2013 Aug;9(8):1661-72. DOI:10.4161/hv.24715 |
| | CpG1018 Preparation Products And Raw materials |
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