Org 30276

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Org 30276 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Fuan Bio  
Tel: 15002819872
Email: 2845971812@qq.com
Org 30276 Basic information
Product Name:Org 30276
Synonyms:Org 30276;APTAA LHRH;APTAALHRH;APTAA-LHRH;Org 31276;Org31276;Org-31276
CAS:83539-08-6
MF:C69H91Cl2N17O14
MW:1453.47
EINECS:
Product Categories:
Mol File:83539-08-6.mol
Org 30276 Structure
Org 30276 Chemical Properties
density 1.458±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka3.698±0.10(predicted)
Safety Information
MSDS Information
Org 30276 Usage And Synthesis
UsesORG 30276 (APTAA-LHRH) is a potent GnRH antagonist that effectively reduces serum LH and FSH levels in male rats. ORG 30276 significantly decreases unoccupied pituitary GnRH receptors, leading to suppressed gonadotropin secretion. ORG 30276 treatment results in a considerable reduction in mRNA levels of gonadotropin beta-subunits in the pituitary gland. ORG 30276's effects on gonadotropin dynamics can be selectively reversed by the replacement of specific sex steroids, with androgens being particularly effective for the FSH beta-subunit mRNA levels.
References[1] Gonadotropin gene expression and secretion in gonadotropin-releasing hormone antagonist-treated male rats: effect of sex steroid replacement DOI:10.1210/endo-126-6-3204
Org 30276 Preparation Products And Raw materials
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