| Company Name: |
Zhende Chemical Technology (Shanghai) Co., Ltd.
|
| Tel: |
15601952568 |
| Email: |
sales4@myuchem.com |
| Products Intro: |
Product Name:1-Cyclohexyl-3-(cyclopropylmethyl)-N-((3-methylisoxazol-5-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide , hNPR1 inhibitor JS-11
CAS:1394592-04-1
Purity:0.97 Package:1g;5g;10g
|
| Company Name: |
Bide Pharmatech Ltd.
|
| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:1-Cyclohexyl-3-(cyclopropylmethyl)-N-((3-methylisoxazol-5-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide
CAS:1394592-04-1
Purity:95% Package:10mg;25mg;50mg;100mg;250mg Remarks:BD01418154
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:JS11
CAS:1394592-04-1
Package:10mg;50mg
|
|
| | 1-Cyclohexyl-3-(cyclopropylmethyl)-2,3-dihydro-N-[(3-methyl-5-isoxazolyl)methyl]-2-oxo-1H-benzimidazole-5-carboxamide Basic information |
| | 1-Cyclohexyl-3-(cyclopropylmethyl)-2,3-dihydro-N-[(3-methyl-5-isoxazolyl)methyl]-2-oxo-1H-benzimidazole-5-carboxamide Chemical Properties |
| Boiling point | 617.4±55.0 °C(Predicted) | | density | 1.286±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 12.95±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | 1-Cyclohexyl-3-(cyclopropylmethyl)-2,3-dihydro-N-[(3-methyl-5-isoxazolyl)methyl]-2-oxo-1H-benzimidazole-5-carboxamide Usage And Synthesis |
| Uses | JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1. JS11 ameliorates the pruritus in mouse models[1]. | | References | [1] Hoon MA, et al., Compositions and methods for the inhibition of pruritus. WO2019090039. |
| | 1-Cyclohexyl-3-(cyclopropylmethyl)-2,3-dihydro-N-[(3-methyl-5-isoxazolyl)methyl]-2-oxo-1H-benzimidazole-5-carboxamide Preparation Products And Raw materials |
|