- Cirsimaritin
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- $52.00 / 1mg
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2026-04-22
- CAS:6601-62-3
- Min. Order:
- Purity: 99.89%
- Supply Ability: 10g
- cirsimaritin
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- $7.00 / 1KG
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2019-09-02
- CAS:6601-62-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | cirsimaritin Basic information |
| Product Name: | cirsimaritin | | Synonyms: | 4',5-Dihydroxy-6,7-dimethoxyflavone;5-Hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one;6-Methoxygenkwanin;Scrophulein;Skrofulein;Cirsimaritin >=90% (LC/MS-ELSD);4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-;Circimaritin | | CAS: | 6601-62-3 | | MF: | C17H14O6 | | MW: | 314.29 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 6601-62-3.mol |  |
| | cirsimaritin Chemical Properties |
| Melting point | 257 °C | | Boiling point | 563.6±50.0 °C(Predicted) | | density | 1.402±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: 10 mM | | form | A solid | | pka | 6.34±0.40(Predicted) | | color | Light yellow to light brown | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | InChI | 1S/C17H14O6/c1-21-14-8-13-15(16(20)17(14)22-2)11(19)7-12(23-13)9-3-5-10(18)6-4-9/h3-8,18,20H,1-2H3 | | InChIKey | ZIIAJIWLQUVGHB-UHFFFAOYSA-N | | SMILES | COc1cc2OC(=CC(=O)c2c(O)c1OC)c3ccc(O)cc3 | | LogP | 1.970 (est) |
| Hazard Codes | T,N | | Risk Statements | 25-50 | | Safety Statements | 45-61 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| | cirsimaritin Usage And Synthesis |
| Uses | Cirsimaritin is a flavonoid obtained from Cirsium japonicum var. maackii pappus and is effective as an anti-inflammatory agent as well as antioxidant. | | Definition | ChEBI: A dimethoxyflavone that is flavone substituted by methoxy groups at positions 6 and 7 and hydroxy groups at positions 5 and 4' respectively. | | Biological Activity | Cirsimaritin has been shown to inhibit tumor cell growth and induce mitochondrial apoptosis in GBC-SD cells. It was proposed th at cirsimaritin-induced reactive oxygen species is the trigger for ER stress and down-regulate the phosphorylation of Akt. | | in vivo | Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds[1]. |
| | cirsimaritin Preparation Products And Raw materials |
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