Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:LP-6 CAS:1629736-79-3 Package:10mg;50mg
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Product Name: | LP-6 | Synonyms: | LP-6;1H-Imidazole-2-butanamide, 4-(2,5-difluorophenyl)-N-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]-γ-[[[(3S,4R)-4-fluoro-3-pyrrolidinyl]methyl][(2S)-2-hydroxy-1-oxopropyl]amino]-β,β-dimethyl-1-(phenylmethyl)-, (γR)- | CAS: | 1629736-79-3 | MF: | | MW: | 694.74 | EINECS: | | Product Categories: | | Mol File: | 1629736-79-3.mol |  |
Boiling point | 883.985±65.00 °C(Press: 760.00 Torr)(predicted) | density | 1.356±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | pka | 13.518±0.20(predicted) |
Uses | LP-6 is a Drug-Linker Conjugates for ADC, and can be used for synthesis of ADCs. LP-6 consists of an Eg5 inhibitor and a linker[1]. | References | [1] Karpov AS, et al. Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization. ACS Med Chem Lett. 2019 Dec 3;10(12):1674-1679. DOI:10.1021/acsmedchemlett.9b00468 |
| LP-6 Preparation Products And Raw materials |
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