ALPHA-AMANITIN

ALPHA-AMANITIN Suppliers list

Company Name:	Hebei Kangcang new material Technology Co., LTD
Tel:	+8619133911216
Email:	Jany1001@kangcang.com.cn
Products Intro:	Product Name:alpha-Amanitin CAS:23109-05-9 Purity:99% Package:10g;9USD\|100g;70USD

Company Name:	career henan chemical co
Tel:	+86-0371-86658258
Email:	sales@coreychem.com
Products Intro:	Product Name: ALPHA-AMANITIN CAS: 23109-05-9 Purity:99% Package:1KG;7USD

Company Name:	Wuhan Boyuan Import & Export Co., LTD
Tel:	+8615175982296
Email:	Mike@whby-chem.com
Products Intro:	Product Name:α-Amanitin CAS:23109-05-9 Purity:99.96% Package:50mg;60USD\|100mg;45USD

Company Name:	Hubei xin bonus chemical co. LTD
Tel:	86-13657291602
Email:	linda@hubeijusheng.com
Products Intro:	Product Name:ALPHA-AMANITIN CAS:23109-05-9 Purity:0.99 Package:5KG;1KG

Company Name:	Hebei shuoxi biotechnology co. LTD
Tel:	+8613081092107
Email:
Products Intro:	Product Name:α-Amanitin CAS:23109-05-9 Purity:99.8% Package:1KG;60USD

ALPHA-AMANITIN manufacturers

ALPHA-AMANITIN Basic information

Product Name:	ALPHA-AMANITIN
Synonyms:	Aids004473;Aids-004473;AMANITIN, a-(RG);AMANITIN, a-(RG)(CALL);cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4-8)-sulfide(R)-S-oxide;alpha-AMantine, froM AManita Phalloides;AMANITIN, A-;ALPHA-AMANITIN
CAS:	23109-05-9
MF:	C39H54N10O14S
MW:	918.98
EINECS:	245-432-2
Product Categories:	Alkaloids;DNA-RNA Transcription RegulatorsCell Signaling and Neuroscience;Gene Regulation and Expression;Cell Signaling and Neuroscience;Mushroom;Toxins and Venoms;Enzyme Inhibitors;Enzyme Inhibitors by Type;Other;Miscellaneous Enzyme;inhibitor
Mol File:	23109-05-9.mol

ALPHA-AMANITIN Chemical Properties

Melting point	254-255 °C(lit.)
alpha	D20 +191°
Boiling point	1622.2±65.0 °C(Predicted)
density	1.1626 (rough estimate)
refractive index	1.7400 (estimate)
storage temp.	−20°C
solubility	H₂O: 1.0 mg/mL
form	powder
pka	9.63±0.70(Predicted)
color	white to light yellow
Water Solubility	Soluble to 5 mM in ethanol and to 5 mM in water
Merck	13,370
BRN	1071138

Safety Information

Hazard Codes	T+
Risk Statements	26/27/28-33-26/28
Safety Statements	36/37/39-45-36/37-28
RIDADR	UN 3462 6.1/PG 2
WGK Germany	3
RTECS	BD6195000
F	8-10-18-21
HazardClass	6.1(a)
PackingGroup	I
HS Code	2934999090
Hazardous Substances Data	23109-05-9(Hazardous Substances Data)
Toxicity	LD50 i.p. in albino mice: 0.1 mg/kg (Wieland, Wieland)

MSDS Information

Provider	Language
SigmaAldrich	English

ALPHA-AMANITIN Usage And Synthesis

Uses	α-Amanitin has been used: for inducing transcriptional arrest in NT2 cells prior to immunofluorescence assay to induce nephrotoxicity in mice renal tissues to induce and analyse genotoxicity in mice bone marrow cells by cell viability assay, comet assay and chromosomal aberration assay
Biological Activity	α-amanitin, the most deleterious toxin of a. phalloides to humans, inhibits rna polymerase ii (rnapii), causing hepatic and renal failure.
Biochem/physiol Actions	The major toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but does not inhibit RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.
storage	Store at -20°C

ALPHA-AMANITIN Preparation Products And Raw materials

Tag:ALPHA-AMANITIN(23109-05-9) Related Product Information

gamma-amanitin ALPHA-AMANITIN OLEATE alpha-Amanitin, 1-l-aspartic acid- METHYL ALPHA-AMANITIN OLEATE 6'-O-methyl alpha-amanitin 4,9-dioxo-5,10-diazatetradecane ALPHA-AMANITIN