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Cholesterol-undecanoate-glucose conjugate

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Company Name: Cayman Chemical Company  
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Products Intro: Product Name:CholesterolUndecanoateGlucose Conjugate
Company Name: Neobioscience Co., Ltd.  
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Products Intro: Product Name:CholesterolUndecanoateGlucose Conjugate
Cholesterol-undecanoate-glucose conjugate Basic information
Product Name:Cholesterol-undecanoate-glucose conjugate
Synonyms:Cholesterol-undecanoate-glucose conjugate
CAS:
MF:
MW:0
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Mol File:Mol File
Cholesterol-undecanoate-glucose conjugate Structure
Cholesterol-undecanoate-glucose conjugate Chemical Properties
solubility DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 2 mg/ml
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MSDS Information
Cholesterol-undecanoate-glucose conjugate Usage And Synthesis
DescriptionCholesterol-undecanoate-glucose conjugate is a glucose-based lipid conjugate that has been used in the generation of brain-targeted liposomes.1 It forms a stable, ordered bilayer with phospholipids with the glucose moiety facing outward for the purpose of being recognized by glucose transporter 1 (GLUT1) on the blood-brain barrier. Intravenous and intranasal administration of fluorescently labeled liposomes containing cholesterol-undecanoate-glucose conjugate and encapsulating the antimalarial artesunate (Item No. 11817) and the methylated pyrazine ligustrazine (Item No. 29658) induces increased brain fluorescence intensity and a reduced infection rate in a mouse model of P. falciparum-induced cerebral malaria when compared with fluorescently labeled non-cholesterol-undecanoate-glucose conjugate-containing liposomes encapsulating artesunate and ligustrazine.WARNING This product is not for human or veterinary use.
References[1] YA TIAN. Establishment and evaluation of glucose-modified nanocomposite liposomes for the treatment of cerebral malaria.[J]. ACS Central Science, 2022: 318. DOI: 10.1186/s12951-022-01493-8
Cholesterol-undecanoate-glucose conjugate Preparation Products And Raw materials
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