| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Endonuclease III
Purity:>=90% (SDS-PAGE) Package:10μg Remarks:E0526
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Remarks:90% (SDS-PAGE), recombinant, expressed in E. coli overproducing strain, buffered aqueous glycerol solution, ≥10,000 units/mg protein
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| Company Name: |
BD Biosciences
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| Tel: |
1 877 232 8995 U.S. orders |
| Email: |
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| Products Intro: |
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| Company Name: |
R & D Systems
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| Tel: |
612 379 2956 |
| Email: |
info@rndsystems.com |
| Products Intro: |
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| | E COLI ENDONUCLEASE III Basic information |
| Product Name: | E COLI ENDONUCLEASE III | | Synonyms: | NTH PROTEIN;THYMINE GLYCOL-DNA GLYCOSYLASE;E COLI NTH PROTEIN;E COLI ENDONUCLEASE III;ENDO III;ENDONUCLEASE III;Endonuclease III from Escherichia coli | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![E COLI ENDONUCLEASE III Structure]() |
| | E COLI ENDONUCLEASE III Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| | E COLI ENDONUCLEASE III Usage And Synthesis |
| Biochem/physiol Actions | Endo III, product of the nth gene, is an iron-sulfur containing DNA repair enzyme. It possesses DNA glycosylase activity with broad substrate specificity for mutated pyrimidine derivatives especially thymine glycol (Tg) but also for 5-hydroxycytosine and 5,6-dihydrothymine. In addition, it has an apurinic/apyrimidinic (AP) lyase activity which cleaves the DNA backbone by β elimination. Endo III protects E. coli cells from radiation damage caused by x-ray and UV irradiation and its activity overlaps the activity of endonuclease VIII. When overexpressed, it can also protect E.coli cells from alkylation defects caused by methylmethanesulphonate. |
| | E COLI ENDONUCLEASE III Preparation Products And Raw materials |
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