Fmoc-Thr-Obzl manufacturers
- Fmoc-L-Thr-Obzl
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- $0.00 / 1kg
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2024-04-28
- CAS:73724-48-8
- Min. Order: 1kg
- Purity: 98%;99%
- Supply Ability: 1 ton+
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| Fmoc-Thr-Obzl Basic information |
Product Name: | Fmoc-Thr-Obzl | Synonyms: | FMOC-L-THR(BZL)-OH;FMOC-THREONINE(BZL)-OH;N-ALPHA-FMOC-O-BENZYL-L-THREONINE;N-A-FMOC-O-BENZYL-L-THREONINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYL-L-THREONINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-BENZYL-L-THREONINE;N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-O-BENZYL-L-THREONINE;Fmoc-L-Thr-OBzl | CAS: | 73724-48-8 | MF: | C26H25NO5 | MW: | 431.48 | EINECS: | | Product Categories: | Amino Acids | Mol File: | 73724-48-8.mol | |
| Fmoc-Thr-Obzl Chemical Properties |
Boiling point | 656.9±55.0 °C(Predicted) | density | 1.257±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,2-8°C | pka | 10.34±0.46(Predicted) | InChIKey | WQYIETDVEJEHCP-OSPHWJPCSA-N | SMILES | C(OCC1=CC=CC=C1)(=O)[C@H]([C@H](O)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| Fmoc-Thr-Obzl Usage And Synthesis |
Synthesis | Fmoc(OTIPS) benzyl ester (0.87 g, 1.48 mmol) is dissolved in 7.4 mL dry CH2Cl2 under an argon atmosphere. The solution is cooled to 0°C and 7.4 mL of 40% (v/v) Piperidine solution in dry CH2Cl2 is added dropwise. After 15 min of stirring at 0°C, the mixture is concentrated in vacuo at 25°C to an oil and put immediately onto the silica column (cyclohexane/EtOAc 5: 1 + 0.5% NEt3, elution of product with 1: 1 + 0.5% NEt3). The yield of Fmoc-Thr-Obzl is 0.44 g (1.20 mmol, 81%) as a colorless oil.
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| Fmoc-Thr-Obzl Preparation Products And Raw materials |
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