- 3-Bromophthalide
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- $10.00 / 1KG
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2021-10-09
- CAS:6940-49-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20 tons
- 3-Bromophthalide
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- $15.00 / 1KG
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2021-07-13
- CAS:6940-49-4
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 3-Bromophthalide Basic information |
| Product Name: | 3-Bromophthalide | | Synonyms: | 3-BROMO-1(3H)-ISOBENZOFURANONE;3-BROMOPHTHALIDE;3-bromo-1(3h)-isobenzofuranon;3-Bromophtalide;3-Bromophthalide97%;1(3H)-Isobenzofuranone, 3-bromo-;BROMOPHTHALIDE;3-BROMOPHTHALIDE 98+% | | CAS: | 6940-49-4 | | MF: | C8H5BrO2 | | MW: | 213.03 | | EINECS: | 230-084-6 | | Product Categories: | Phthalides;bc0001 | | Mol File: | 6940-49-4.mol |  |
| | 3-Bromophthalide Chemical Properties |
| Melting point | 86°C | | Boiling point | 138 °C / 3mmHg | | density | 1.768±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | soluble in Methanol | | form | powder to crystal | | color | White to Light yellow to Light orange | | InChIKey | CLMSHAWYULIVFQ-UHFFFAOYSA-N | | CAS DataBase Reference | 6940-49-4(CAS DataBase Reference) | | EPA Substance Registry System | 1(3H)-Isobenzofuranone, 3-bromo- (6940-49-4) |
| | 3-Bromophthalide Usage And Synthesis |
| Synthesis | 3-Bromophthalide is produced by reacting phthalide with N-bromosuccinimide in carbon tetrachloride solution.
Ten grams (0.075 mole) of phthalide (Note 1), 13.3 g. (0.075 mole) of N-bromosuccinimide, and 200 ml. of dry carbon tetrachloride are refluxed for 30 minutes in a 500-ml. flask carrying a reflux condenser equipped with a drying tube containing Drierite. The reaction mixture is exposed to the light of an ordinary 100-watt unfrosted light bulb placed 6–8 in. from the flask. The end of the reaction is indicated by the disappearance of N-bromosuccinimide from the bottom of the flask and accumulation of succinimide at the top of the reaction mixture. The succinimide is removed by filtration and the filtrate concentrated under atmospheric pressure to 15–20 ml. Cooling of this concentrate followed by filtration gives 12–13 g. (75–81%) of crude 3-bromophthalide, m.p. 74–80°. The crude material, when recrystallized from cyclohexane, gives colorless plates, m.p. 78–80°.
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| | 3-Bromophthalide Preparation Products And Raw materials |
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