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| | 3-TERT-BUTYL-4-HYDROXYANISOLE Basic information |
| | 3-TERT-BUTYL-4-HYDROXYANISOLE Chemical Properties |
| Melting point | 58-64 °C | | Boiling point | 269℃ | | density | 1.009 | | vapor pressure | 1.33 hPa (105 °C) | | refractive index | 1.4708 (estimate) | | Fp | 110 °C | | storage temp. | Store below +30°C. | | solubility | ethanol: soluble1g/10 mL, clear, colorless to faint yellow or tan | | form | Powder/Waxy Solid | | pka | 11.83±0.18(Predicted) | | color | White to off-white | | Water Solubility | 610-3400mg/L at 27-29℃ | | BRN | 1867499 | | LogP | 1-2.82 at 25-27℃ | | CAS DataBase Reference | 121-00-6(CAS DataBase Reference) | | EPA Substance Registry System | Phenol, 2-(1,1-dimethylethyl)-4-methoxy- (121-00-6) |
| | 3-TERT-BUTYL-4-HYDROXYANISOLE Usage And Synthesis |
| Uses | antioxidant in foods (beverages, gum, ice cream, fruits, cereals), cosmetics, topical medications, animal feeds, petroleum
products, jet fuels, rubber, plastics, paints, glues. | | Uses | An antioxidant stabilizer of fats that has shown carcinogenicity at high doses | | Uses | 3-tert-Butyl-4-hydroxyanisole may be used as a pharmaceutical reference standard for the determination of the analyte in plasma samples using high-resolution capillary gas chromatography-mass spectrometry with selective ion monitoring. | | Definition | ChEBI: 3-tert-butyl-4-hydroxyanisole is an aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group. It has a role as an antioxidant and a human xenobiotic metabolite. It is a member of phenols and an aromatic ether. | | General Description | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
3-tert-Butyl-4-hydroxyanisole is a synthetic antioxidant, widely used as a food additive to prevent oxidative deterioration of fats and oils. | | Flammability and Explosibility | Non flammable | | Purification Methods | Fractionally distil the phenol in vacuo, then pass it as a solution in CHCl3 through alumina, and evaporate the eluate. Recrystallise the residue from pet ether. [Beilstein 6 IV 6013.] |
| | 3-TERT-BUTYL-4-HYDROXYANISOLE Preparation Products And Raw materials |
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