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CITRININ

CITRININ Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:CITRININ
CAS:518-75-2
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:518-75-2
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:CITRININ
CAS:518-75-2
Company Name: J & K SCIENTIFIC LTD.  
Tel: 400-666-7788 +86-10-82848833
Email: jkinfo@jkchemical.com;market6@jkchemical.com
Products Intro: Product Name:Citrinin, 98%
CAS:518-75-2
Purity:98% Package:1MG;25MG;5MG
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 86-21-50328103 * 801、802、803、804 Mobile:18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:CITRININ
CAS:518-75-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
CITRININ Basic information
Product Name:CITRININ
Synonyms:(3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid;,(3r-trans)-;3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-;3H-2-Benzopyran-7-carboxylic acid, 4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-, (3R-trans)-;4,6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3h-2-benzopyran-7-carboxylicaci;6-dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-(3r-trans)-3h-2-benzopyran-7-carboxylicaci;8-Hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid;Citriain
CAS:518-75-2
MF:C13H14O5
MW:250.25
EINECS:208-257-2
Product Categories:Active Pharmaceutical Ingredients;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;antibiotic
Mol File:518-75-2.mol
CITRININ Structure
CITRININ Chemical Properties
Melting point 175°C (dec.)
alpha D18 -37.4° (c = 1.15 in alc.)
Boiling point 313.38°C (rough estimate)
density 1.37
refractive index 1.4560 (estimate)
Fp 2℃
storage temp. 2-8°C
form Crystalline Powder or Flakes
color Yellow
Merck 13,2351
BRN 5282243
CAS DataBase Reference518-75-2(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 23/24/25-40-36/37/38
Safety Statements 26-36/37/39-45-22-7/9
RIDADR UN 3462 6.1/PG 3
WGK Germany 3
RTECS DJ2275000
HazardClass 6.1(a)
PackingGroup II
HS Code 29419090
ToxicityLD50 in mice, rats (mg/kg): 35, 67 i.p. (Ambrose, De Eds)
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
CITRININ Usage And Synthesis
Chemical Propertiesyellow crystalline powder or flakes
Chemical PropertiesAntimycin (A3C26H36N2O9) and (Antimycin A1) C28H40N2O9 are crystalline solids.
UsesAntibiotic substance produced by a white spore aspergilus which has been placed under the species name Aspergillus niveus. Also produced in small quantities by Penicillium citrinum.
Usesantibacterial
UsesCitrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigate, and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption of mitochondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity.
UsesCitrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigated and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption of mitochondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity.
Potential ExposureSpecific uses for antimycin A were not found, however, antimycin A1, and antimycin A3 are reported to be antibiotic substances produced by streptomyces for use as a fungicide, possible insecticide and miticide. Registered as a pesticide in the U.S.
First aidMove victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. Keep victim warm and quiet. Effects of exposure (inhalation, ingestion or skin contact) to substance may be delayed. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.
ShippingUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
CITRININ Preparation Products And Raw materials
Tag:CITRININ(518-75-2) Related Product Information
Ethyl propenyl ether Allylacetic acid TRANS-2-HEPTEN-1-OL 2-methylpent-2-en-1-ol 2,3-DIMETHYL-2-HEXENE 1-METHOXY-1,3-BUTADIENE 3-METHYL-2,5-HEXADIENE 2-PROPYL-2-HEPTENAL 3-HEPTEN-1-OL TRANS-2-PENTEN-1-OL 2-METHYL-2-HEXENOIC ACID CIS-4-HEPTENAL CITRININ 3-METHYL-3-HEPTEN-2-ONE 4-METHYL-1,4-HEPTADIENE 2,4-Dimethyl-1,4-pentadiene TRANS-2-HEXEN-1-OL 3-ETHYL-4-METHYL-2-PENTENE