| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Company Name: |
SIGMA-RBI |
| Tel: |
800 736 3690 (Orders) |
| Email: |
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| | Anti-IL2, Anti-Lymphokine, Anti-TCGF Basic information |
| | Anti-IL2, Anti-Lymphokine, Anti-TCGF Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | mouse |
| WGK Germany | WGK 1 | | Storage Class | 13 - Non Combustible Solids |
| | Anti-IL2, Anti-Lymphokine, Anti-TCGF Usage And Synthesis |
| Uses | Anti-interleukin-2 antibody may be used in immunohistochemistry at a working concentration of 8-25 μg/ml in human peripheral blood leukocytes. For flow cytometry a concentration of 25 μg/ml may be used. The antibody is suitable for IL-2 neutralization assays. | | Biological Activity | Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/ST at as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle. |
| | Anti-IL2, Anti-Lymphokine, Anti-TCGF Preparation Products And Raw materials |
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