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Guaiacol Suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-571-85586718 +86(0)13336195806
Products Intro: Product Name:Guaiacol
Purity:98.5%(Min.,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:90-05-1
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Guangzhou PI PI Biotech Inc
Tel: ; +8618371201331;+8618371201331
Products Intro: Product Name:Guaifenesin EP impurity A
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Remarks:2-methoxyphenol (guaiacol)
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418679
Products Intro: Product Name:Guaiacol
Purity:99.9% Package:1KG;5USD
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Products Intro: Product Name:Guaiacol
Purity:HPLC>=98% Package:20mg

Guaiacol manufacturers

  • Guaiacol
  • $0.00 / KG
  • 2022-01-25
  • CAS:90-05-1
  • Min. Order: 100g
  • Purity: 98%+
  • Supply Ability: 100kg
  • Guaiacol
  • $1.00 / Kg/Bag
  • 2022-01-13
  • CAS:90-05-1
  • Min. Order: 1Kg/Bag
  • Purity: 99.75% HPLC
  • Supply Ability: 5000tons/year
  • Guaiacol
  • $10.00 / KG
  • 2021-12-11
  • CAS:90-05-1
  • Min. Order: 1KG
  • Purity: 99.9%
  • Supply Ability: 500MT/month

Related articles

  • The uses of Guaiacol
  • Guaiacol is present in wood smoke, resulting from the pyrolysis of lignin. The compound contributes to the flavor of many subs....
  • Nov 14,2019
Guaiacol Basic information
Chemical properties Application Preparative methods Toxicity
Product Name:Guaiacol
Product Categories:ANASTIL;Pharmaceutical Intermediates;Aromatics Compounds;Antioxidant;Biochemistry;Aromatics;Aromatic Ethers
Mol File:90-05-1.mol
Guaiacol Structure
Guaiacol Chemical Properties
Melting point 26-29 °C (lit.)
Boiling point 205 °C (lit.)
density 1.129 g/mL at 25 °C (lit.)
vapor density 4.27 (vs air)
vapor pressure 0.11 mm Hg ( 25 °C)
refractive index n20/D 1.543(lit.)
Fp 180 °F
storage temp. 2-8°C
solubility H2O: insoluble
form Liquid After Melting
pka9.98(at 25℃)
color Clear colorless to light yellow
PH5.4 (10g/l, H2O, 20℃)
Odor Threshold0.0074ppm
Water Solubility 17 g/L (15 ºC)
FreezingPoint 28℃
Sensitive Air Sensitive
Merck 14,4553
JECFA Number713
BRN 508112
Stability:Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference90-05-1(CAS DataBase Reference)
NIST Chemistry ReferencePhenol, 2-methoxy-(90-05-1)
EPA Substance Registry SystemGuaiacol (90-05-1)
Safety Information
Hazard Codes Xn,T,Xi
Risk Statements 22-36/38
Safety Statements 26
WGK Germany 1
RTECS SL7525000
Autoignition Temperature750 °C
Hazard Note Toxic/Irritant
HazardClass 6.1(b)
PackingGroup II
HS Code 29095010
Hazardous Substances Data90-05-1(Hazardous Substances Data)
ToxicityLD50 orally in rats: 725 mg/kg (Taylor)
MSDS Information
1-Hydroxy-2-methoxybenzene English
SigmaAldrich English
ACROS English
ALFA English
Guaiacol Usage And Synthesis
Chemical propertiesIt appears as white or slightly yellow crystals or colorless to pale yellow transparent oily liquid. It has a special aromatic smell. It is slightly soluble in water and benzene. It is easily soluble in glycerol. It is miscible with ethanol, ether, chloroform, oil and glacier acetic acid.
ApplicationUsed for pharmaceuticals, dyes and spices intermediates
Mainly used for the preparation of coffee, vanilla, fumigation and tobacco flavor.
Used for the synthesis of dyes, also used as analytical reagents
In medicine, it can be used for the manufacture of calcium guaiacol sulfonate; in the spice industry, it is used the manufacture of vanillin and artificial musk; Used for test copper, hydrocyanic acid and nitrite
Preparative methodsIt can be obtained by diazotization and hydrolysis of anthranium anisole.
Obtained from fractionated of wood oil.
In the nature of guaiacol is presented in the guaiacum or pine oil. In the creosote oil obtained from wood dry distillation, guaiacol is the major ingredient. This product could be obtained through fractional distillation of creosote oil. Japan Osaka Refining Company takes o-nitrochlorobenzene as raw material, first synthesizes o-nitroanisole, and then reduces it to o-anisidine, and finally obtains the goods. China's production method is roughly the same. Ingredient consumption quota: 1250 kg / t of amino-containing anisole, 1500 kg / t of sulfuric acid (93%), 700 kg / t of sodium nitrite and 400 kg / t of copper sulfate.
ToxicityLD50:900 mg / kg (rat, subcutaneous).
LD50: 3.7 mg / kg (rabbit, intravenously).
Oral administration of large amount can stimulate the esophagus and stomach, resulting in heart failure, collapse and death.
DescriptionGuaiacol has a characteristic sweet odor. It is slightly phenolic. Guaiacol is obtained from hardwood tar or synthetically from onitrophenol via o-anisidine.
Chemical PropertiesGuaiacol has a characteristic sweet odor. It is slightly phenolic.
Chemical PropertiesLight Yellow Oil
OccurrenceDetected in the distillation product from guaiac resin; guaiacol is found in castoreum oil, in the essential oil from fowers of Pandanus odoratissimus L , in the distillation waters of orange leaves, in the essential oil of Ruta Montana L and in the essential oil of tobacco leaves Also reported found in lemon peel oil, bog blueberry, asparagus, cabbage, celery, onion, chive, tomato, peppermint oil, rye bread, Parmesan cheese, butter, smoked fsh, meats, barley, dried bonito, malt, hardwood smoke, cognac, beer, brandy, rum, whiskies, sherry, grape wines, cocoa, coffee, tea, peanuts, popcorn, soybeans, avocado, beans, mushroom, sesame seed, mango, tamarind, rice dill, licorice, corn oil, cuttlefsh and other sources
UsesGuaiacol is a precursor of vanillin and santalidol (a synthetic sandal- wood fragrance). it is obtained from wood tar by the destructive distillation of hardwood, by the distillation of the phenol fraction of coal tar, or through the use of o-dichlorobenzene. it is processed to yield vanillin.
UsesSynthetic flavors, medicine (expectorant).
UsesA phenolic natural product and reducing co-substrate for COX reactions.
DefinitionChEBI: A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.
Aroma threshold valuesDetection: 3 to 31 ppb; aroma characteristics at 1.0%: phenolic, smoky, spicy, medicinal, vanilla, savory meaty, woody with a bourbon whiskey casky nuance.
Taste threshold valuesTaste characteristics at 2.0 ppm: woody, phenolic, bacon, savory, smoky and medicinal.
General DescriptionColorless to amber crystals or liquid. Density (of solid) 1.129 g / cm3. Solidifies at 28°C (82.4°F), but may remain liquid for a long time even at a much lower temperature. Slightly water soluble . Soluble in aqueous sodium hydroxide. Used medicinally as an expectorant. Used, because of its anti-oxidant properties, as an anti-skinning agent for paints.
Air & Water ReactionsSensitive to air and light (darkens). Slightly water soluble.
Reactivity ProfileGuaiacol may react with oxidizing materials. Guaiacol forms salts readily with bases.
HazardToxic by ingestion and skin absorption.
Fire HazardGuaiacol is combustible.
Biochem/physiol ActionsGuaiacol, along with 2,4,6-trichloroanisole, is responsible for cork taint in wine. A method has been developed for extraction and quantitation of the two compounds.
Chemical SynthesisObtained from hardwood tar or synthetically from o-nitrophenol via o-anisidine.
Purification MethodsCrystallise guaiacol from *benzene/pet ether or distil it in a vacuum. [Beilstein 6 H 768, 6 IV 5563.]
Tag:Guaiacol(90-05-1) Related Product Information
Tectorigenin (-)-GUAIOL 3β,5,14-Trihydroxy-5β-bufa-20,22-dienolide Iriflophene 2-(2-methoxyphenoxy)propane-1,3-diol Guaifenesin EP Impurity C 1,3-Bis(2-methoxyphenoxy)-2-propanol XANTHENE-9-CARBOXYLIC ACID Sesamol Guaiacol glycidyl ether 3-(o-Methoxyphenoxy)-1,2-propanediol, Guaiacol Glyceryl Ether, Robitussin,GUAIACOL GLYCERYL ETHER SIGMA REFERENCE STANDARD guaiacol sulphdnate potassium,Potassium guaiacol sulphonate Zeaxanthin 4-Methoxyphenol GUM GUAIAC GUAIACYLGLYCEROL-BETA-GUAIACYL ETHER 3,4-dihydro-5,6,7-trimethoxy-2-naphthoic acid 3,4-DIMETHOXYBENZOYL CHLORIDE