| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
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| | ANTI HUMAN PPAR-DELTA Basic information |
| Product Name: | ANTI HUMAN PPAR-DELTA | | Synonyms: | Anti-PPARD antibody produced in rabbit;Anti-PPAR δ (Isoform 1) antibody produced in goat;ANTI HUMAN PPAR-DELTA;ANTI-NR1C2;ANTI-PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA;ANTI-PPAR-BETA;ANTI-PPAR DELTA;Anti-FAAR | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI HUMAN PPAR-DELTA Structure]() |
| | ANTI HUMAN PPAR-DELTA Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | - | | Storage Class | 10 - Combustible liquids |
| | ANTI HUMAN PPAR-DELTA Usage And Synthesis |
| Uses | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper) | | Biological Activity | PPARD is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors th at bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR delta and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. |
| | ANTI HUMAN PPAR-DELTA Preparation Products And Raw materials |
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