- 5-HEXEN-1-OL
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- $0.00 / 1KG
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2025-10-29
- CAS:821-41-0
- Min. Order: 1KG
- Purity: 0.90/0.98
- Supply Ability: 500tons
- 1-Hexen-6-ol
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- $8.80 / 1kg
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2025-10-13
- CAS:821-41-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100kg
- 5-Hexen-1-Ol
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- $5.00 / 1KG
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2025-05-26
- CAS:821-41-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
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| | 5-Hexen-1-ol Chemical Properties |
| Melting point | <-20°C | | Boiling point | 78-80 °C/25 mmHg (lit.) | | density | 0.834 g/mL at 25 °C (lit.) | | FEMA | 4351 | 5-HEXENOL | | refractive index | n20/D 1.435(lit.) | | Fp | 117 °F | | storage temp. | Sealed in dry,2-8°C | | solubility | 18.6g/l | | form | Liquid | | pka | 15.17±0.10(Predicted) | | Specific Gravity | 0.846 | | color | Clear colorless | | PH | 7 (H2O) | | Odor | green | | Odor Type | green | | biological source | synthetic | | Water Solubility | Miscible with water. | | JECFA Number | 1623 | | BRN | 1236458 | | Stability: | Volatile | | InChI | 1S/C6H12O/c1-2-3-4-5-6-7/h2,7H,1,3-6H2 | | InChIKey | UIZVMOZAXAMASY-UHFFFAOYSA-N | | SMILES | OCCCCC=C | | LogP | 1.50 | | CAS DataBase Reference | 821-41-0(CAS DataBase Reference) | | EPA Substance Registry System | 5-Hexen-1-ol (821-41-0) |
| Hazard Codes | F | | Risk Statements | 10 | | Safety Statements | 16-24/25 | | RIDADR | UN 1987 3/PG 3 | | WGK Germany | 1 | | F | 9 | | Hazard Note | Flammable | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29052290 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1B |
| | 5-Hexen-1-ol Usage And Synthesis |
| Background |
Enol is an important fine chemical, such as isophytol, folyl alcohol, etc. It can be further used as a critical intermediate for synthesizing medicines, pesticides, essences, spices and the like with high economic added values. It has a large market demand. 5-Hexen-1-ol is a common organic synthesis and medical intermediate and an essential raw material for chemical engineering and medicine.
| | Chemical Properties | Clear, colorless liquid with a green aroma. | | Uses | 5-Hexen-1-ol is used in cyclization to a tetrahydropyran by phenylselenoetherification. It is also used as a building block in synthetic chemistry. Further, it is used to prepare 6-bromo-hex-1-ene by reaction with phosphorus tribromide. | | Preparation | 5-hexen-1-ol may be prepared from 2-(chloromethyl)tetrahydropyran according to the literature procedure for the preparation of 4-penten-1-ol (Brooks, L. A.; Snyder, H. R. Org. Synth. Coll. Vol. III 1955, 698). | | Application | 5-Hexen-1-ol is used as a food flavouring agent and as a raw material in organic synthesis for cyclisation to other compounds such as tetrahydropyran via phenylselenide etherification. | | Aroma threshold values | Medium strength odor; recommend smelling in a 10.00% solution or less | | Synthesis |
6-bromo-1-hexene is used as a raw material, and tetrabutylammonium bromide is used as a catalyst. In an acetonitrile solvent, it is heated to react with potassium acetate. The mixed solution is then cooled to room temperature (18-25°C), the reaction solution is concentrated under reduced pressure, and then water is added to dissolve; methyl tert-butyl ether is added and stirred to separate the layers, the water layer is extracted once with methyl tert-butyl ether, the organic phases are combined and filtered, and the filtrate is concentrated under reduced pressure. The concentrated solution begins to hydrolyze, and 15% alkaline aqueous solution and methanol are added to the concentrated solution. The mixture is stirred at room temperature to dissolve each other; after the hydrolysis is completed, the methanol is concentrated under reduced pressure. After concentration to dryness, the system begins to separate into layers, with an upper organic phase and a lower aqueous phase. The aqueous phase is extracted twice with dichloromethane, and the combined organic phases are concentrated under reduced pressure to obtain 5-Hexen-1-ol.
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| | 5-Hexen-1-ol Preparation Products And Raw materials |
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