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Dibenzoyl-L-tartaric acid

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Products Intro: Product Name:Dibenzoyl-L-tartaric acid
CAS:2743-38-6
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CAS:2743-38-6
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Products Intro: Product Name:L-(-)-DIBENZOYL-(D)-TARTARIC ACID
CAS:2743-38-6
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Products Intro: Product Name:Dibenzoyl-L-tartaric acid
CAS:2743-38-6
Purity:99% Package:1KG;10.00;USD

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Dibenzoyl-L-tartaric acid Basic information
Product Name:Dibenzoyl-L-tartaric acid
Synonyms:2,3-bis(benzoyloxy)tartaric acid;BENZOYL-L-TARTARICACID;(2R,3R)-2,3-Bis-benzoyloxy-succinic acid;L(-)-O,O'-Dibenzoyl-tataric acid;(L)-DIDETA (Dibenzoyl-(L)-tartaric acid monohyderate);DIBENZOYL-L-TARARIC ACID;L-Tartaric acid 2,3-dibenzoate;(-)-O,Oμ-Dibenzoyl-L-tartaric acid, L-Tartaric acid 2,3-dibenzoate
CAS:2743-38-6
MF:C18H14O8
MW:358.3
EINECS:220-374-0
Product Categories:Chiral Compound;chiral;straight chain compounds;Anilines, Amides & Amines;Bromine Compounds;Carboxylic Acids (Chiral);Pharmaceutical Intermediates;FINE Chemical & INTERMEDIATES;Chiral Compounds;Chiral Building Blocks;Synthetic Organic Chemistry;CHIRAL CHEMICALS;Hydroxy Acids & Deriv.;Aromatics;Chiral Reagents;Miscellaneous Reagents;2743-38-6
Mol File:2743-38-6.mol
Dibenzoyl-L-tartaric acid Structure
Dibenzoyl-L-tartaric acid Chemical Properties
Melting point 152-155 °C(lit.)
Boiling point 234 °C / 7mmHg
density 1.3806 (rough estimate)
vapor pressure 0Pa at 20℃
refractive index -116 ° (C=1, EtOH)
storage temp. Refrigerator
solubility DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka1.85±0.25(Predicted)
form Solid or Crystalline Powder
color Off-white to orange to pale brown
Optical Rotation[α]20/D 116°, c = 9 in ethanol
Water Solubility Slightly soluble in water.
BRN 709854
InChI1S/C18H14O8/c19-15(20)13(25-17(23)11-7-3-1-4-8-11)14(16(21)22)26-18(24)12-9-5-2-6-10-12/h1-10,13-14H,(H,19,20)(H,21,22)/t13-,14-/m1/s1
InChIKeyYONLFQNRGZXBBF-ZIAGYGMSSA-N
SMILESOC(=O)[C@H](OC(=O)c1ccccc1)[C@@H](OC(=O)c2ccccc2)C(O)=O
LogP1.01 at 20℃
CAS DataBase Reference2743-38-6(CAS DataBase Reference)
EPA Substance Registry SystemButanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)- (2743-38-6)
Safety Information
Hazard Codes Xi
Risk Statements 36
Safety Statements 26-36
WGK Germany 3
RTECS WW8070000
3-9
TSCA TSCA listed
HS Code 29181990
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Dam. 1
Skin Sens. 1
MSDS Information
ProviderLanguage
L(-)-Dibenzoyl-L-tartaric acid English
SigmaAldrich English
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Dibenzoyl-L-tartaric acid Usage And Synthesis
DescriptionDibenzoyl-L-tartaric acid is a kind of white crystalline powder, and odorless, mildly bitter flavor, be slightly soluble in water, and pH value is 3-4, in acid, dissolves in ethanol and acetone and other organic solvent. Be widely used in chiral separation of racemic amine compounds. Because it is cheap, has stable properties, and is easy to recycle, it has good industrial application value.
Chemical PropertiesDibenzoyl-L-tartaric acid is white to light yellow crystal powde
Uses(-)-Dibenzoyl-L-tartaric acid, anhydrous is used as a reagent used to produce chiral salts. Also used as organic chemical synthesis intermediate.
Application Dibenzoyl-L-tartaric acid plays a crucial role in the resolution of chiral compounds, particularly in the separation of enantiomers of racemic mixtures.
Flammability and ExplosibilityNot classified
Safety ProfileDibenzoyl-L-tartaric acid is an eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
SynthesisA synthetic method of Dibenzoyl-L-tartaric acid includes the following steps: with L-tartaric acid and benzoyl chloride as raw materials, copper sulfate as a catalyst and toluene as a solvent, carrying out reaction to prepare L-dibenzoyl tartaric anhydride, carrying out hydrolysis with an equal amount of water and toluene to obtain the L-dibenzoyl tartaric acid, wherein the toluene serving as the solvent, as well as the water and the toluene in the hydrolysis step, can be repeatedly utilized.
References[1] Patent: CN104496806, 2016, B. Location in patent: Paragraph 0099-0102
[2] Journal of Chemical Research, Miniprint, 1984, # 5, p. 1518 - 1530
Dibenzoyl-L-tartaric acid Preparation Products And Raw materials
Raw materialsL(+)-Tartaric acid-->Benzoyl chloride-->Copper(II) sulfate-->Toluene
Preparation ProductsButanedioic acid, 2,3-bis(benzoyloxy)-, 1-methyl ester, (2R,3R)--->2-ChloroMandelic Acid Methyl Ester
Tag:Dibenzoyl-L-tartaric acid(2743-38-6) Related Product Information
D(-)-Tartaric acid Benzoyl chloride Folic acid DL-Tartaric acid Benzoyl peroxide PHENYLGLYOXAL MONOHYDRATE Ethyl 2-(Chlorosulfonyl)acetate (+)-Dibenzoyl-D-tartaric acid L(+)-Tartaric acid Methyl benzoylformate Voriconazole Glycine (-)-Di-p-toluoyl-L-tartaric acid Dibenzoyltartaric acid 2,3-Di-O-para-toluoyl-D-tartaric acid (-)-Dibenzoyl-L-tartaric acid monohydrate Di-p-anisoyl-D-tartaric acid Di-p-anisoyl-L-tartaric acid