ChemicalBook > Product Catalog >API >Antiparasitic drugs >Anthelmintics >PYRVINIUM PAMOATE

PYRVINIUM PAMOATE

PYRVINIUM PAMOATE Suppliers list
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:PYRVINIUM PAMOATE
CAS:3546-41-6
Purity:95%-99% Package:1kg;1USD
Company Name: Klong Industrial Co., Ltd
Tel: 0086-519-68231162
Email: info@klongchem.com
Products Intro: Product Name:Pyrvinium embonate
CAS:3546-41-6
Purity:99% Package:25kgs
Company Name: Changzhou Ansciep Chemical Co., Ltd.
Tel: +86 519 86305871
Email: sales@ansciepchem.com
Products Intro: Product Name:Pyrvinium embonate
CAS:3546-41-6
Purity:98% Package:100g, 500g, 1kg, 25kg, 50kg, 200kg Remarks:Good quality; Large stock; Hot sale
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Email: sales@chemdad.com
Products Intro: Product Name:PYRVINIUM PAMOATE
CAS:3546-41-6
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: 15319487004
Email: 1015@dideu.com
Products Intro: Product Name:Pyrvinium Pamoate
CAS:3546-41-6
Purity:99.0%

PYRVINIUM PAMOATE manufacturers

  • PYRVINIUM PAMOATE
  • $5.00 / KG
  • 2021-11-08
  • CAS:3546-41-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100 Tons
  • Pyrvinium Pamoate
  • $0.00-0.00 / Kg
  • 2020-04-28
  • CAS:3546-41-6
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 500 tons
PYRVINIUM PAMOATE Basic information
Pharmacology and mechanism of action Indications Side effects Preparations References
Product Name:PYRVINIUM PAMOATE
Synonyms:6-(dimethylamino)-2-(2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl)-1-quinoliniu;alnoxin;altolat;methyl-,saltwith4,4’-methylenebis(3-hydroxy-2-naphthoicacid)(2:1);molevac;neo-oxypate;pamovin;pirviniumpamoate
CAS:3546-41-6
MF:C75H70N6O6
MW:1151.39
EINECS:222-596-3
Product Categories:POVAN
Mol File:3546-41-6.mol
PYRVINIUM PAMOATE Structure
PYRVINIUM PAMOATE Chemical Properties
Melting point 210-215° (softens at 190°)
Boiling point 829.27°C (rough estimate)
density 1.0104 (rough estimate)
refractive index 1.6400 (estimate)
storage temp. 2-8°C
solubility DMSO: >10mg/mL
form powder
color red
EPA Substance Registry SystemPyrvinium pamoate (3546-41-6)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38-40
Safety Statements 26-36
WGK Germany 3
HS Code 2933492250
MSDS Information
PYRVINIUM PAMOATE Usage And Synthesis
Pharmacology and mechanism of action Pyrvinium is a quaternary ammonium derivative of a cyanine dye with marked effect against Enterobius vermicularis.
The mechanism of action is not well known. The drug inhibits oxidative metabolism in the worms and interferes with the absorption of glucose in intestinal helminths. Since most intestinal worms are dependent on anaerobic carbohydrate metabolism, this may be an important action of the drug[1].
 
IndicationsInfections caused by Enterobius vermicularis. Pyrvinium is largely replaced today by more effective and safer drugs such as albendazole and mebendazole.
 
Side effects Gastrointestinal disturbances such as nausea, vomiting, dyspepsia, indigestion and abdominal pain are frequent. Allergic reactions and photosensitivity have been reported. Pyrvinium stains the stool bright red and may stain clothing if vomiting occurs. Patients should be informed about this.
 
PreparationsPyrvinium pamoate (embonate): 450 mg of the pamoate is equivalent to 300 mg of pyrvinium.
• Povanyl ® (Parke-Davis). Oral solution 10 mg pyrvinium per ml. Tablets 50 mg pyrvinium.
• Vanquin® (Parke-Davis). Oral solution 10 mg pyrvinium per ml. Tab pyrvinium.
References1. Buchanan RA, Barrow WB, Heffelfinger JC, Kinkel AW, Smith TC, Turner JL (1974). Pyrvinium pamoate. Clin Pharmacol Ther, 16, 716–719.
Usesanthelmintic
Brand namePovan (Parke-Davis).
General DescriptionOdorless bright orange or orange-red to brownish red or almost black fluffy powder. Melting point 210-215°C. Insoluble in water. Tasteless.
Air & Water ReactionsInsoluble in water.
Reactivity ProfilePYRVINIUM PAMOATE is light sensitive. Incompatible with strong oxidizing agents, strong acids and bases .
Fire HazardFlash point data for PYRVINIUM PAMOATE are not available; however, PYRVINIUM PAMOATE is probably combustible.
PYRVINIUM PAMOATE Preparation Products And Raw materials
Tag:PYRVINIUM PAMOATE(3546-41-6) Related Product Information
3-hydroxynaphthalene-2-carbaldehyde 1,1'-METHYLENEDI-2-NAPHTHOL PYRVINIUM PAMOATE 2,5-DIMETHYL-1-PHENYLPYRROLE 1-methylquinolinium EMBONIC ACID 1,2,5-TRIMETHYLPYRROLE 1-ETHYLNAPHTHALENE 2-HYDROXY-3-METHYLBENZALDEHYDE 2-VINYLQUINOLINE Pyridinium acetate 6-Aminoquinoline AMMONIUM SALICYLATE 1-PHENYLPYRROLE 2-Naphthalenemethanol toluic acid 2,4-Dimethylpyrrole 2,5-Dimethyl-1H-pyrrole