Sugammadex sodium

Sugammadex sodium Suppliers list
Company Name: Chengdu Aslee Biopharmaceuticals, Inc.
Tel: +86 28 85305008
Email: may.yang@asleechem.com
Products Intro: Product Name:Sugammadex Sodium
CAS:343306-79-6
Purity:99% Package:1KG;USD
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: 008615858145714
Email: fandachem@gmail.com
Products Intro: Product Name:Sugammadex sodium
CAS:343306-79-6
Package:as customers' requirement
Company Name: Hubei XinRunde Chemical Co., Ltd.
Tel: +8615102730682; +8618874586545
Email: bruce@xrdchem.cn
Products Intro: Product Name:Sugammadex soidum 343306-79-6
CAS:343306-79-6
Purity:98% Package:1KG;50USD
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:Sugammadex Sodium
CAS:343306-79-6
Purity:0.99 Package:5G,10G,25G,50G,100G,250G,1KG
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Sugammadex
CAS:343306-79-6
Purity:98% Package:100mg/500mg/1g

Sugammadex sodium manufacturers

  • Sugammadex sodium
  • $16.00 / g
  • 2021-11-30
  • CAS:343306-79-6
  • Min. Order: 500g/Bag
  • Purity: 99%
  • Supply Ability: 100KG
  • Sugammadex Sodium
  • $99.00 / KG
  • 2021-11-15
  • CAS:343306-79-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 5ton/Month
  • Sugammadex sodium
  • $0.00 / KG
  • 2021-11-09
  • CAS:343306-79-6
  • Min. Order: 2KG
  • Purity: 99% up, High Density
  • Supply Ability: 20 tons
Sugammadex sodium Basic information
Product Name:Sugammadex sodium
Synonyms:ORG-25969/SugaMMadex;Sugammadex Na;ORG;Sugammadex IMP;Sugammadex soidum 343306-79-6;Sugammadex sodium iMpurity;6A,6B,6C,6D,6E,6F,6G,6H-octakis-S-(2-Carboxyethyl)-6A,6B,6C,6D,6E,6F,6G,6H-octathio-γ-cyclodextrin Sodium Salt;Sugammadex Sodium salt
CAS:343306-79-6
MF:C72H104Na8O48S8
MW:2177.97
EINECS:
Product Categories:API
Mol File:343306-79-6.mol
Sugammadex sodium Structure
Sugammadex sodium Chemical Properties
storage temp. Inert atmosphere,Room Temperature
CAS DataBase Reference343306-79-6
Safety Information
MSDS Information
Sugammadex sodium Usage And Synthesis
DescriptionTo facilitate tracheal intubation, mechanical ventilation, and surgical access, NMB agents are frequently used as non-anesthetic adjuncts in surgical procedures. Sugammadex is able to function as a pharmacologic sink of rocuronium and vecuronium, another non-depolarizing neuromuscular blocker, without the cardiovascular adverse effects experienced with reversal agents that directly interact with the cholinergic system. The γ-cyclodextrin has been designed to enhance binding of the guest by incorporating acidic side chains to promote an electrostatic interaction with the positive nitrogen of the blocker. Starting with γ-cyclodextrin, these side chains are readily installed by first halogenating with iodine or bromine to provide a handle for nucleophilic displacement with either 3-mercaptopropionic acid in the presence of sodium hydride or with 3-mercaptopropionic acid methyl ester and cesium carbonate. The latter requires hydrolysis with sodium hydroxide to generate sugammadex sodium.
Chemical PropertiesColorless, orthorhombic crystals from DMF + water. d 1.446. Solubility in water.
OriginatorOrganon (Netherlands)
UsesSugammadex Sodium is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents and may have many potential peri-operative benefits.
UsesReversal agent for neuromuscular blocking drugs.
DefinitionChEBI: An organic sodium salt that is the octasodium salt of sugammadex. Used for reversal of neuromuscular blockade induced by rocuronium and vecuronium in adults undergoing surgery.
Brand nameBridion
Side effectsThe most common adverse effects included coughing, movement, vomiting, dry mouth, dysgeusia, hypotension, parosmia, and a sensation of changed temperature.Sugammadex is recommended for the reversal of neuromuscular blockade induced by rocuronium or vecuronium; it should not be used with other steroidal blocking agents since safety and efficacy data are not available for these situations. It should also not be partnered with non-steroidal neuromuscular blockers such as succinylcholine or benzylisoquinolinium-based drugs. Since sugammadex is predominantly cleared by the kidneys, care should be taken when administering this reversal agent in patients with renal impairment.
Sugammadex sodium Preparation Products And Raw materials
Tag:Sugammadex sodium(343306-79-6) Related Product Information
Sulbactam Impurity 6 Sugammadex Impurity 52 octakis(6-chloro-6-deoxy)-γ-cyclodextrin 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-(2-hydroxypropyl)-β-cyclodextrin Sugammadex Entacapone Tolvaptan 2-(DIETHYLAMINO)-N-(2,4-DIMETHYLPHENYL)ACETAMIDE 2-(DiethylaMino)-N-(2,4-diMethylphenyl)acetaMide Hydrochloride 2-chloro-N-(2,4-dimethylphenyl)acetamide Lidocaine Impurity Tianeptine Impurity 6,11-Dihydro-6-methyl-dibenzo[c,f][1,2]thiazepin-11-ol 5,5-Dioxide Tianeptine intermediate Avanafil Impurity Tianeptine Impurity lignocaine N-oxide SUGAMMADEX