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| | Arterolane Basic information |
| Product Name: | Arterolane | | Synonyms: | Arterolane;OZ 277;Arterolane
(OZ277;RBx 11160);Dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decane]-4-acetamide, N-(2-amino-2-methylpropyl)-, cis-;-[1,2,4]trioxolane-5’cis-N-(2-Amino-2-methylpropyl)dispiro[cyclohexane-1,3’-tricyclo[3.3.1.13,7]decane]-4-acetamide | | CAS: | 664338-39-0 | | MF: | C22H36N2O4 | | MW: | 392.53 | | EINECS: | | | Product Categories: | | | Mol File: | 664338-39-0.mol |  |
| | Arterolane Chemical Properties |
| Melting point | 160-162℃ | | Boiling point | 572.2±45.0 °C(Predicted) | | density | 1.20 | | storage temp. | Store at -20°C, protect from light, stored under nitrogen | | solubility | DMSO: soluble | | form | A solid | | pka | 16.70±0.46(Predicted) |
| | Arterolane Usage And Synthesis |
| Definition | ChEBI: Arterolane is an oxaspiro compound that is dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.1(3,7)]decane] substituted by a 2-[(2-amino-2-methylpropyl)amino]-2-oxoethyl group at position 4s. Its maleic acid salt is used as an antimalarial drug in combination with piperaquine. It has a role as an antimalarial and an antiplasmodial drug. It is a member of adamantanes, a secondary carboxamide, a primary amino compound, a trioxolane and an oxaspiro compound. It is a conjugate base of an arterolane(1+). |
| | Arterolane Preparation Products And Raw materials |
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