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lopinavir+ritonavir

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Company Name: Beijing HuaMeiHuLiBiological Chemical   
Tel: 010-56205725
Email: waley188@sohu.com
Products Intro: Product Name:lopinavir+ritonavir
lopinavir+ritonavir Basic information
Product Name:lopinavir+ritonavir
Synonyms:lopinavir+ritonavir
CAS:369372-47-4
MF:C74H96N10O10S2
MW:1349.74504
EINECS:
Product Categories:
Mol File:369372-47-4.mol
lopinavir+ritonavir Structure
lopinavir+ritonavir Chemical Properties
BCS Class2/2
Safety Information
MSDS Information
lopinavir+ritonavir Usage And Synthesis
DefinitionChEBI: Kaletra is a mixture containing lopinavir and ritonavir. It is a prescription medicine that is used with other antiretroviral medicines to treat Human Immunodeficiency Virus-1 (HIV-1) infection in adults and children 14 days of age and older. It has a role as an antiviral drug, a HIV protease inhibitor and an anticoronaviral agent. It contains a lopinavir and a ritonavir.
Clinical UseRecently, the U.S. FDA has approved the release of lopinavir/ritonavir combination in patients who have not responded to other regimens for treatment of HIV. The product is available in a soft-gelatin capsule containing 133.3 mg of lopinavir and 33.3 mg of ritonavir as well as in oral solutions containing 80 mg/mL of lopinavir and 20 mg/mL of ritonavir. The small amount of ritonavir is not expected to have antiretroviral activity; rather, the ritonavir is meant to increase the plasma concentrations of lopinavir by inhibiting lopinavir's metabolism by CYP3A4 (ritonavir acts as a booster). These drugs, in combination with other antiretroviral agents, have been approved for use in adults as well as in patients between the ages of 6 months and 12 years. This is the first PI to be indicated for the very young.
lopinavir+ritonavir Preparation Products And Raw materials
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