| | (-)-TRAMADOL Basic information |
| Product Name: | (-)-TRAMADOL | | Synonyms: | (-)-2-[(DIMETHYLAMINO)METHYL]-1-(3-METHOXYPHENYL)CYCLOHEXANOL;Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1S,2R)- | | CAS: | 181289-59-8 | | MF: | C16H25NO2 | | MW: | 263.38 | | EINECS: | | | Product Categories: | | | Mol File: | 181289-59-8.mol |  |
| | (-)-TRAMADOL Chemical Properties |
| Boiling point | 388.1±22.0 °C(Predicted) | | density | 1.047±0.06 g/cm3(Predicted) | | pka | 14.47±0.40(Predicted) |
| | (-)-TRAMADOL Usage And Synthesis |
| Definition | ChEBI: (S,S)-tramadol is a 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have S-configuration; the (S,S)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold lower analgesic potency than the (R,R)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist and a serotonin uptake inhibitor. It is a conjugate base of a (S,S)-tramadol(1+). It is an enantiomer of a (R,R)-tramadol. |
| | (-)-TRAMADOL Preparation Products And Raw materials |
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