| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:16:0 Lyso PA (sodium salt)
CAS:17618-08-5
Purity:>=98% Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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| Tel: |
400-6206333 13167063860 |
| Email: |
anhua.mao@aladdin-e.com |
| Products Intro: |
Product Name:1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
CAS:17618-08-5
Purity:>99% Package:100mg/RMB 3913.90;25mg/RMB 1441.90;250mg/RMB 7199.00
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1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT) manufacturers
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| | 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT) Basic information |
| Product Name: | 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT) | | Synonyms: | 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT);16:0 LYSO PA SODIUM SALT;1-Palmitoyl Lysophosphatidic Acid (sodium salt) Exclusive;16:0 LPA;16:0 Lyso PA;1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE (SODIUM SALT);16:0 LYSO PA;16:0 LPA;PA(16:0/0:0);PA(16:0/0:0);1-Palmitoyl-lyso-Phosphatidic acid Na salt | | CAS: | 17618-08-5 | | MF: | C19H37Na2O7P | | MW: | 454.45 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: <.05 mg/ml; DMSO: <.05 mg/ml; Ethanol: <.05 mg/ml | | form | A crystalline solid | | color | White to off-white |
| | 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT) Usage And Synthesis |
| Description | 1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of Pseudomonas aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+. | | Uses | (2R)-2-Hydroxy-3-(phosphonooxy)propyl hexadecanoate Sodium Salt is used in the test kit for screening colorectal adenoma. | | References | [1] KYOKO NOGUCHI Takao S Satoshi Ishii. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family.[J]. The Journal of Biological Chemistry, 2003, 278 28: 25600-25606. DOI: 10.1074/jbc.m302648200
[2] MOOLENAAR W H. LPA: a novel lipid mediator with diverse biological actions.[J]. Trends in Cell Biology, 1994, 4 6: 213-219. DOI: 10.1016/0962-8924(94)90144-9
[3] K A KROGFELT. Specific phospholipids enhance the activity of beta-lactam antibiotics against Pseudomonas aeruginosa.[J]. Journal of Antimicrobial Chemotherapy, 2000, 46 3: 377-384. DOI: 10.1093/jac/46.3.377 |
| | 1-PALMITOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATE(SODIUM SALT) Preparation Products And Raw materials |
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