| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:5-Oxo-ETE;5-Oxo-(6E,8Z,11Z,14Z)-6,8,11,14-eicosatetraenoicacid
CAS:106154-18-1
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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| Tel: |
0717-6449896 13886658719 |
| Email: |
root@zhongyitai.com |
| Products Intro: |
Product Name:5-Oxo-6(E),8(Z),11(Z),14(Z)-Eicosatetraenoic acid
CAS:106154-18-1
Purity:98+% Package:100ug
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:5-Oxo-ETE
CAS:106154-18-1
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Product Name: | 5-KETE | | Synonyms: | 5-OXO-6E,8Z,11Z,14Z-EICOSATETRAENOIC ACID;5-OXOETE;5-KETE;5-KETOEICOSA-6E,8Z,11,Z14Z-TETRAENOIC ACID;5-Oxo-(6E,8Z,11Z,14Z)-6,8,11,14-eicosatetraenoicacid;5-OxoETE Lipid Maps MS Standard;MEASLHGILYBXFO-XTDASVJISA-N;5-OxoETE MaxSpec Standard | | CAS: | 106154-18-1 | | MF: | C20H30O3 | | MW: | 318.45 | | EINECS: | | | Product Categories: | | | Mol File: | 106154-18-1.mol |  |
| | 5-KETE Chemical Properties |
| Boiling point | 495.0±45.0 °C(Predicted) | | density | 0.980±0.06 g/cm3(Predicted) | | storage temp. | Store at -80°C | | solubility | DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | | form | Liquid. | | pka | 4.59±0.10(Predicted) |
| | 5-KETE Usage And Synthesis |
| Description | 5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase. It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM. 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.
5-OxoETE MaxSpec® standard is a quantitative grade standard of 5-oxoETE that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 5-oxoETE MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. | | Uses | 5-oxo-ETE is a compound that stimulates neutrophil degranulation. | | Definition | ChEBI: 5-oxo-ETE is an oxoicosatetraenoic acid having a 5-oxo group; and (6E)-, (8Z), (11Z)- and (14Z)-double bonds. It has a role as a human metabolite, a mouse metabolite and an immunomodulator. It is functionally related to an icosa-6,8,11,14-tetraenoic acid. It is a conjugate acid of a 5-oxo-ETE(1-). | | Biological Activity | Potent oxoeicosanoid (OXE) receptor agonist (EC 50 = 0.33 nM). Chemoattractant for both neutrophils and eosinophils and induces transendothelial migration of eosinophils. |
| | 5-KETE Preparation Products And Raw materials |
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