Propargyl-PEG4-bromide

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Products Intro: Product Name:Propargyl-PEG4-bromide
CAS:1308299-09-3
Purity:99% HPLC Package:5KG;1KG
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Products Intro: Product Name:Propargyl-PEG4-Br
CAS:1308299-09-3
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:Propargyl-PEG4-bromide
CAS:1308299-09-3
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Products Intro: Product Name:Propargyl-PEG4-bromide
CAS:1308299-09-3
Purity:0.99 Package:10MG,50MG,100MG,1G
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Products Intro: Product Name:Propargyl-PEG4-Br
CAS:1308299-09-3
Package:100mg

Propargyl-PEG4-bromide manufacturers

  • Propargyl-PEG4-Br
  • Propargyl-PEG4-Br pictures
  • $0.00 / 100mg
  • 2024-10-28
  • CAS:1308299-09-3
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  • Supply Ability: 10g
Propargyl-PEG4-bromide Basic information
Product Name:Propargyl-PEG4-bromide
Synonyms:Propargyl-PEG4-bromide;Alkyne-PEG4-Br;PROPARGYL-PEG4-BR;3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-;1-Bromo-3,6,9,12-tetraoxapentadec-14-yne;Propargyl-PEG4-Br/3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-;3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]prop-1-yne
CAS:1308299-09-3
MF:C11H19BrO4
MW:295.17
EINECS:
Product Categories:peg
Mol File:1308299-09-3.mol
Propargyl-PEG4-bromide Structure
Propargyl-PEG4-bromide Chemical Properties
Boiling point 334.3±32.0 °C(Predicted)
density 1.269±0.06 g/cm3(Predicted)
form Liquid
color Light yellow to yellow
Safety Information
MSDS Information
Propargyl-PEG4-bromide Usage And Synthesis
DescriptionPropargyl-PEG4-bromide is a crosslinker that can be used in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage with azides. The bromide (Br) acts as a good leaving group for nucleophilic substitution reactions.
UsesPropargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50Non-cleavable Linker; PEGs
References[1] Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2.
Propargyl-PEG4-bromide Preparation Products And Raw materials
Tag:Propargyl-PEG4-bromide(1308299-09-3) Related Product Information
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