| Company Name: |
Angel Pharmatech, Ltd.
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| Tel: |
17317130613 |
| Email: |
3358272972@qq.com |
| Products Intro: |
Product Name:Pumaprazole
CAS:158364-59-1
Purity:98% HPLC Package:1G;5G
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| | Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester Basic information |
| Product Name: | Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester | | Synonyms: | Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester;PUMAPRAZOLE;inhibit,Proton Pump,BY 841,Pumaprazole,BY841,Inhibitor;Methyl (2-(((2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino)methyl)-3-methylphenyl)carbamate | | CAS: | 158364-59-1 | | MF: | C19H22N4O2 | | MW: | 338.4 | | EINECS: | | | Product Categories: | | | Mol File: | 158364-59-1.mol | ![Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester Structure](CAS/20180529/GIF/158364-59-1.gif) |
| | Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester Chemical Properties |
| density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 13.67±0.70(Predicted) | | color | Light yellow to yellow |
| | Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester Usage And Synthesis |
| Description | Pumaprazole has been abandoned
in favor of a pharmacologically better
follow up compound presently under development
at Byk Gulden. The WHO decided to
label the APAs by the stem syllable “-prazole”
in order “to maintain the number of stems at
a manageable level”, irrespective of the completely
different (i.e., reversible vs. covalent)
modes of drug – target interactions by APAs and
PPIs (WHO decision communicated on Nov. 30,
1995). Unfortunately, this pharmacologically
misleading but legally binding decision will confuse
the rational use and differential perception
of APAs vs. PPIs in the future and counteracts
the effort for an unambiguous terminology in
pharmacology. It should be noted that the terms
APAs and PPIs have been coined specifically
to make a clearly recognizable distinction between
the two chemically and mechanistically
different classes of drugs. |
| | Carbamic acid,N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]-,methyl ester Preparation Products And Raw materials |
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