Alkyne-ethyl-PEG1-t-Butyl ester

Alkyne-ethyl-PEG1-t-Butyl ester Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Alkyne-ethyl-PEG1-Boc;Alkyne-ethyl-PEG1-t-butyl ester
CAS:2100306-55-4
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
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Products Intro: Product Name:Alkyne-ethyl-PEG1-t-Butyl ester
CAS:2100306-55-4
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Aladdin Scientific
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Products Intro: Product Name:Alkyne-ethyl-PEG1-t-Butyl ester
CAS:2100306-55-4
Purity:98% Package:$781.9/250mg;$1351.9/500mg;$2041.9/1g;Bulk package Remarks:98%
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
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Products Intro: Product Name:Alkyne-ethyl-PEG1-t-Butyl ester
CAS:2100306-55-4
Purity:98% Package:100mg;250mg;1g;5g;
Company Name: Shaanxi Xinyan Bomei Biotechnology Co., Ltd.  
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Products Intro: Product Name:Alkyne-ethyl-PEG1-t-Butyl ester
CAS:2100306-55-4
Purity:95% HPLC Package:1g;5g;10g;25g;100g;1kg
Alkyne-ethyl-PEG1-t-Butyl ester Basic information
Product Name:Alkyne-ethyl-PEG1-t-Butyl ester
Synonyms:Alkyne-ethyl-PEG1-t-Butyl ester;Alkyne-ethyl-PEG1-Boc;Propanoic acid, 3-(3-butyn-1-yloxy)-, 1,1-dimethylethyl ester
CAS:2100306-55-4
MF:C11H18O3
MW:198.26
EINECS:
Product Categories:
Mol File:2100306-55-4.mol
Alkyne-ethyl-PEG1-t-Butyl ester Structure
Alkyne-ethyl-PEG1-t-Butyl ester Chemical Properties
Boiling point 258.1±20.0 °C(Predicted)
density 0.972±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
Alkyne-ethyl-PEG1-t-Butyl ester Usage And Synthesis
DescriptionAlkyne-ethyl-PEG1-t-Butyl ester has an alkyne group and a t-butyl protected carboxyl group. The alkyne reacts with azide compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage. Thecarboxyl group group can be deprotected under mild acidic conditions.
UsesAlkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Alkyne-ethyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Alkyne-ethyl-PEG1-t-Butyl ester Preparation Products And Raw materials
Tag:Alkyne-ethyl-PEG1-t-Butyl ester(2100306-55-4) Related Product Information

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