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ZORUBICIN HCL

ZORUBICIN HCL Suppliers list
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: 15336106720
Email: 1017@dideu.com
Products Intro: Product Name:Zorubicin Hydrochloride
CAS:36508-71-1
Purity:99% Package:1KG;1USD
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-89586680 18192503167
Email: 1005@dideu.com
Products Intro: Product Name:ZORUBICIN HCL USP/EP/BP
CAS:36508-71-1
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
Company Name: Dideu Industries Group Limited
Tel: 029-88380327; 17691182729
Email: Service@dideu.com
Products Intro: Product Name:ZORUBICIN HCL USP/EP/BP
CAS:36508-71-1
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
Company Name: LGM Pharma  
Tel: 1-(800)-881-8210
Email: inquiries@lgmpharma.com
Products Intro: Product Name:Zorubicin Hydrochloride
CAS:36508-71-1
Purity:Typically NLT 98%
Company Name: ChemStrong Scientific Co.,Ltd  
Tel: 0755-66853366-
Email: sales@chem-strong.com
Products Intro: Product Name:Zorubicin hydrochloride
CAS:36508-71-1
Purity:95% HPLC Package:10mg;25mg;50mg;100mg

ZORUBICIN HCL manufacturers

ZORUBICIN HCL Basic information
Product Name:ZORUBICIN HCL
Synonyms:ZORUBICIN HCL;22050r.p.;benzoicacidhydrazide,3-hydrazonewithdaunorubicin,monohydrochloride;daunorubicin,benzoylhydrazone,monohydrochloride;nsc-164011;rp22,050hydrochloride;rubidaz;rubidazone,monohydrochloride
CAS:36508-71-1
MF:C34H36ClN3O10
MW:682.12
EINECS:253-076-4
Product Categories:
Mol File:36508-71-1.mol
ZORUBICIN HCL Structure
ZORUBICIN HCL Chemical Properties
alpha D20 -50° (c = 0.2 in water)
Safety Information
ToxicityLD50 in mice (mg/kg): 13.66 s.c., 4.42 i.p., 8.50 i.v. (Maral, 1972)
MSDS Information
ZORUBICIN HCL Usage And Synthesis
OriginatorZorubicin Hydrochloride,ZYF Pharm Chemical
UsesAntineoplastic.
UsesZorubicin Hydrochloride is an anthracycline anti-cancer drug related to Daunorubicin (D194500).
Manufacturing Process9.024 g daunorubicin-hydrochloride (its preparation and physicochemical properties have been described in British Patent Specification No 985 598) was dissolved in 800 ml ethanol and mixed with 2.5 ml acetic acid and 2.162 g benzoyl hydrazide and heated for 24 hours at 60°C. On cooling the obtained precipitate was filtered off, washed with 100 ml of ethanol and dried in vacuum at 20°C. It was dissolved in water and small quantity of insoluble product was filtered off, the filtrate was lyophilized. (1-(4-((3-Amino-2,3,6- trideoxy-α,L-lyxohexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12- trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide dihydrochloride (zorubicin) was obtained as red-orange crystalline powder; [α] D 20 = -50° (c=0.2 in water). The compound may be employed in the form of different non-toxic salts such as benzoates, fumarates, maleates, tartrates and so on. The best among these compounds proves to be daunorubicin benzoylhydrazone (rubidazone), which is less cardiotoxic (French Pat. No. 1,578,722 published in 1967, Class CO7d).
Therapeutic FunctionAntineoplastic, Antileukemic
ZORUBICIN HCL Preparation Products And Raw materials
Raw materialsBenzoyl hydrazine-->Daunorubicin hydrochloride-->AMINOGUANIDINE
Tag:ZORUBICIN HCL(36508-71-1) Related Product Information
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