- Isoprenaline sulphate
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- $8.00 / 1kg
-
2024-04-24
- CAS:299-95-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Isoprenaline sulphate
-
- $0.00 / 1kg
-
2023-10-07
- CAS:299-95-6
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20tons
- Isoprenaline sulphate
-
- $1.00 / 10g
-
2022-12-29
- CAS:299-95-6
- Min. Order: 10g
- Purity: 99.5%
- Supply Ability: 1000kg
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| | Isoprenaline sulphate Basic information |
| Product Name: | Isoprenaline sulphate | | Synonyms: | 1-(3,4-DIHYDROXYPHENYL)-2-ISOPROPYLAMINOETHANOL HEMISULFATE SALT;Isoprenaline sulfuric acid;Isoproterenol sulfuric acid;4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol sulfate (2:1);dl-a-3,4-Dihydroxyphenyl-b-iso-propylaminoethanol sulfate;dl-Isoprenaline sulfate;dl-Isoproterenol sulfate | | CAS: | 299-95-6 | | MF: | 2C11H17NO3.H2O4S | | MW: | 520.6 | | EINECS: | 206-085-2 | | Product Categories: | | | Mol File: | 299-95-6.mol |  |
| | Isoprenaline sulphate Chemical Properties |
| Melting point | 180 °C | | form | powder to crystal | | color | White to Almost white | | Water Solubility | almost transparency |
| Risk Statements | 22 | | Safety Statements | 44 | | RTECS | DO2273000 | | HS Code | 29072990 | | Toxicity | dog,LD50,intravenous,50mg/kg (50mg/kg),Drugs in Japan Vol. 6, Pg. 75, 1982. |
| | Isoprenaline sulphate Usage And Synthesis |
| Originator | Isonorin,Smith, Miller and Patch,US,1949 | | Uses | Bronchodilator. | | Manufacturing Process | As described in US Patent 2,308,232, 100 g 3,4-dihydroxy-ω-
chloroacetophenone, 200 cc ethyl alcohol and 200 cc of about 50% aqueous
isopropylamine solution are boiled during 3 hours on the water bath with the
use of a reflux condenser, whereupon neutralizing with diluted sulfuric acid is
carried out and the sulfate, obtained upon cooling, from alcohol of 50% is
recrystallized; its MP is 245°C.
21 g 3,4-dihydroxy-ω-isopropylaminoacetophenone sulfate are hydrogenated
with 50 cc methyl alcohol and 50 cc water, 0.5 g carbon and 3 cc palladium
chloride solution of 2%. After 2 hours the hydrogen absorption comes to a
standstill, after the theoretical quantity of hydrogen has been absorbed. After
concentrating, the isopropylaminomethyl-(3,4-dihydroxyphenyl)carbinolsulfate
crystallizes out. It has a MP of 180°C after refining. | | Brand name | Medihaler-ISO (3M Pharmaceuticals). | | Therapeutic Function | Bronchodilator |
| | Isoprenaline sulphate Preparation Products And Raw materials |
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