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| | 5,6-Dimethylpyridin-2-amine Basic information |
| Product Name: | 5,6-Dimethylpyridin-2-amine | | Synonyms: | 2-AMINO-5,6-DIMETHYLPYRIDINE;5,6-DIMETHYL-PYRIDIN-2-YLAMINE;2-Pyridinamine,5,6-dimethyl-;2-Amino-5,6-dimenthylpyridine;(5,6-dimethyl-2-pyridyl)amine;6-Amino-2,3-dimethylpyridine;5,6-Dimethylpyridin-2-amine, 2-Amino-5,6-dimethylpyridine, 6-Amino-2,3-lutidine;5,6-diMethyl-2-PyridinaMine | | CAS: | 57963-08-3 | | MF: | C7H10N2 | | MW: | 122.17 | | EINECS: | | | Product Categories: | Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Amines;Aromatics;Heterocycles;Pyridines | | Mol File: | 57963-08-3.mol |  |
| | 5,6-Dimethylpyridin-2-amine Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Chloroform, Dichloromethane | | form | Solid | | color | Light Yellow | | InChI | InChI=1S/C7H10N2/c1-5-3-4-7(8)9-6(5)2/h3-4H,1-2H3,(H2,8,9) | | InChIKey | UZAOIPZZPZCFES-UHFFFAOYSA-N | | SMILES | C1(N)=NC(C)=C(C)C=C1 | | CAS DataBase Reference | 57963-08-3 |
| | 5,6-Dimethylpyridin-2-amine Usage And Synthesis |
| Chemical Properties | Light Yellow Low-Melting Solid | | Synthesis | A mixture of 2-amino-5-bromo-6-methylpyridine (561 mg, 3.0 mmol), K2CO3 (1.24 g, 9.0 mmol) and Pd(dppf)Cl2·CH2Cl2 (245 mg, 0.30 mmol) was added to a solution of trimethylboroxine (377 mg, 3.0 mmol) in water (1 mL) and dioxane (10 mL). The mixture was heated at reflux for 3 h. After cooling to rt, the mixture was poured into water (50 mL). The mixture was extracted with diethyl ether (3*50ml), and the combined organic phases were dried (Na2SO4) and concentrated. Purification by chromatography (EtOAc/heptane) gave 5,6-Dimethylpyridin-2-amine as a black-brown solid. Yield: 67 %.
| | References | [1] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 61
[2] Patent: WO2007/51982, 2007, A1. Location in patent: Page/Page column 53 |
| | 5,6-Dimethylpyridin-2-amine Preparation Products And Raw materials |
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