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D-AP5

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D-AP5 Suppliers list
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196
Email: sale04@alfachem.cn
Products Intro: CAS:79055-68-8
Purity:98% Package:5g; 25g; 100g; 500g; 1kg; 25kg
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:D-AP5；D-APV;D-2-Amino-5-phosphonovaleric acid
CAS:79055-68-8
Purity:98.00% Package:10 mg；100 mg；2 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:D-AP5
CAS:79055-68-8
Purity:98% Package:1mg Remarks:V29303
Company Name: LEAP CHEM CO., LTD.
Tel: +86-852-30606658
Email: market18@leapchem.com
Products Intro: Product Name:D-AP5
CAS:79055-68-8
Package:1g; 5g; 25g; 1kg; 5kg; 25kg
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:(R)-(-)-2-Amino-5-phosphonopentanoic acid
CAS:79055-68-8
Purity:98% HPLC Package:100mg，500mg，1g，5g，10g
D-AP5 Basic information
Product Name:D-AP5
Synonyms:D-AP5;D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID;D-2-AMINO-5-PHOSPHONOPENTANOIC ACID;D-(-)-2-AMINO-5-PHOSPHONOVALERIC ACID;D(-)-2-Amino-5-phosphonovaleric acid hydrate;D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID (D-AP5);D(-)-AP-5, D(-)-APV, D-2-Amino-5-phosphonovaleric acid;(R)-2-aMino-5-phosphonopentanoic acid
CAS:79055-68-8
MF:C5H12NO5P
MW:197.13
EINECS:
Product Categories:Glutamate;Glutamate receptor
Mol File:79055-68-8.mol
D-AP5 Structure
D-AP5 Chemical Properties
Melting point approximate 233℃
Boiling point 482.1±55.0 °C(Predicted)
density 1.529±0.06 g/cm3(Predicted)
RTECS RD2513000
storage temp. Store at RT
solubility Soluble to 100 mM in sterile
form White solid
pka2.46±0.10(Predicted)
color White
Water Solubility Soluble in water (100mM)
Sensitive Light Sensitive
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
D-AP5 Usage And Synthesis
DescriptionD-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 μM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (−)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.
Chemical Propertieswhite fine crystalline powder
UsesA competitive NMDA antagonist
General DescriptionActive enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.
Biological ActivityWidely used competitive NMDA antagonist. More active form of AP5. Also agonist at quisqualate-sensitized AP6 site where it is less potent than the L-isomer (L-(+)-2-Amino-5-phosphonopentanoic acid ). Also available as part of the Mixed NMDA Receptor Tocriset™ .
Biochem/physiol ActionsProduct does not compete with ATP.
storageRoom temperature
D-AP5 Preparation Products And Raw materials
Tag:D-AP5(79055-68-8) Related Product Information
12AP ANTI-IGM MU-CHAIN, RAT AP CONJ ANTI-IGG H AND L CHAIN, GOAT AP CONJ DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID D-AP5 5-PHOSPHONOPENTANOIC ACID 4-AMINOBUTYLPHOSPHONIC ACID ANTI-IGG GAMMA-CHAIN, HUMAN AP CONJ ANTI-IGG, HUMAN AP CONJ ANTI-IMMUNOGLOBULIN A, HUMAN, AP ANTI-IGG, MOUSE AP CONJ 16-AP ANTI-IGG(H+L), HUMAN AP CONJ,ANTI-IGG H AND L CHAIN, HUMAN AP CONJ ANTI-IGG(H+L), RABBIT AP CONJ,ANTI-IGG H AND L CHAIN, RABBIT AP CONJ ANTI-IMMUNOGLOBULIN G, BOVINE, F(AB')2, AP ANTI-IGG H AND L CHAIN, HORSE AP CONJ ANTI-IMMUNOGLOBULIN G, CAT, F(AB')2, AP ANTI-IGM MU-CHAIN, HUMAN AP CONJ