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| | 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine Basic information |
| Product Name: | 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine | | Synonyms: | 3,5-DIETHYL-1,2-DIHYDRO-1-PHENYL-2-PROPYLPYRIDINE;1-Phenyl-3,5-diethyl-2-propyl-1,2-dihydropyridine;3,5-diethyl-1,2-dihydro-1-phenyl-2-propyl-pyridin;Pyridine, 3,5-diethyl-1,2-dihydro-1-phenyl-2-propyl-;3,5-DIETHYL-1-PHENYL-2-PROPYL-1,2-DIHYDROPYRIDINE;3,5-Diethyl-1,2-dihydro-1-phen;3,5-Diethyl-1,2-dihydro-1-phenyl-2-n-propylpyridine, tech. 75%;3,5-diethyl-1-phenyl-2-propyl-2H-pyridine | | CAS: | 34562-31-7 | | MF: | C18H25N | | MW: | 255.4 | | EINECS: | 252-091-3 | | Product Categories: | | | Mol File: | 34562-31-7.mol |  |
| | 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine Chemical Properties |
| Boiling point | 125℃/0.5mm | | density | 0.97 | | vapor pressure | 0.003Pa at 25℃ | | Fp | >148 °C | | refractive index | 1.5675 | | storage temp. | 2-8°C | | pka | 0.85±0.70(Predicted) | | Water Solubility | 53.23μg/L at 25℃ | | InChI | InChI=1S/C18H25N/c1-4-10-18-16(6-3)13-15(5-2)14-19(18)17-11-8-7-9-12-17/h7-9,11-14,18H,4-6,10H2,1-3H3 | | InChIKey | IAAASXBHFUJLHW-UHFFFAOYSA-N | | SMILES | C1(CCC)N(C2=CC=CC=C2)C=C(CC)C=C1CC | | LogP | 6.5 at 20℃ | | EPA Substance Registry System | 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine (34562-31-7) |
| | 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine Usage And Synthesis |
| Uses | 3,5-diethyl-1,2-dihydro-1-phenyl-2-propylpyridine (DHP) is the main active ingredient resulting from the condensation reaction of butyraldehyde and aniline. It is a useful research chemical. | | Preparation | 3,5-diethyl-1,2-dihydro-1-phenyl-2-propylpyridine (DHP) was prepared using methods shown below. A 1000 mL four neck flask was equipped with a mechanical stirrer, a reflux condenser, a thermometer, and an addition funnel. An ice-water bath was used to cool the flask as needed. The flask was charged with 86 g de-ionized water, 9.8 g (0.16 mole) acetic acid, and 216 g (3.0 mol) butyraldehyde. With cooling and stirring, 60 g (0.64 mole) aniline was added over a 35-minute period while maintaining the reaction temperature at 20℃. The reaction mixture was stirred for one hour at less than 25℃. The reaction mixture was then heated to 750C and held for two hours. Finally, the reaction mixture was heated to reflux (~90°C) and was held for five hours. The reaction mixture was cooled and the layers were separated. The top, organic layer was distilled through a 14" packed column under reduced pressure. The fraction taken at a head temperature of 140-1430C and 5 mm Hg pressure weighed 104 grams and was analyzed to contain 73% DHP for an overall yield of 46%. |
| | 3,5-Diethyl-1,2-dihydro-1-phenyl-2-propylpyridine Preparation Products And Raw materials |
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