ANTI HUMAN TR-ALPHA

ANTI HUMAN TR-ALPHA Suppliers list
Company Name: Shanghai Huzhen Industrial Co., LTD  
Tel: 021-60345367 13916550749
Email: sales@shzbio.com
Products Intro: Product Name:THRB1
Purity:> 99% Package:50ul/RMB 1138;100ul/RMB 1880;200ul/RMB 2900 Remarks:Thyroid Hormone Receptor beta; Avian erythroblastic leukemia viral (v erb a) oncogene homolog 2; C ERBA 2; C ERBA BETA; c-erbA-2; c-erbA-beta; ERBA 2; ERBA BETA; ERBA2; Erythroblas
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Email:
Products Intro: Purity:affinity isolated antibody, lyophilized powder Remarks:~1 mg/mL, affinity isolated antibody, buffered aqueous solution
Company Name: ABR-Affinity BioReagents  
Tel: 303 278 4535
Email: affinity@bioreagents.com
Products Intro:
Company Name: Peptide Institute, Inc.  
Tel: +81 (0) 72 729 4121
Email: info@peptide.co.jp
Products Intro:
ANTI HUMAN TR-ALPHA Basic information
Product Name:ANTI HUMAN TR-ALPHA
Synonyms:Anti-Nuclear receptor subfamily 1 group A member 1;Anti-c-erbA-1;Anti-C-erbA-alpha;Anti-EAR7;Anti-EAR-7;Anti-THRA antibody produced in rabbit;ERBA-beta;GRTH
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MW:0
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Mol File:Mol File
ANTI HUMAN TR-ALPHA Structure
ANTI HUMAN TR-ALPHA Chemical Properties
storage temp. -20°C
form buffered aqueous glycerol solution
Safety Information
MSDS Information
ANTI HUMAN TR-ALPHA Usage And Synthesis
UsesAnti-THRA antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General DescriptionTHRA (thyroid hormone receptor α) belongs to a family of nuclear receptors, which function as ligand-regulated transcription factors and are called thyroid hormone receptors (TRs). THRA is a predominant mammalian TR isoform. This receptor is highly expressed in central nervous system, myocardium, gastrointestinal tract and skeletal muscle.
Biochem/physiol ActionsConserved lysine in the DNA-binding domain of this receptor functions as a sensor of transcriptional regulation. This lysine is mutated in hepatocellular carcinoma (HCC). Mutations in this protein result in resistance to thyroid hormone, which is alleviated by thyroxine treatment. Population with rs939348 TT polymorphism in this gene show weak relation to increased risk to Alzheimer′s disease. This receptor is also up-regulated in patients with breast cancer.
ANTI HUMAN TR-ALPHA Preparation Products And Raw materials
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