- 5-Fluorooxindole
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- $0.00 / 25kg
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2024-04-12
- CAS:56341-41-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- 5-Fluoro-2-oxindole
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- $5.00 / 1KG
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2024-03-27
- CAS:56341-41-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: g-kg-tons, free sample is available
- 5-Fluoro-2-oxindole
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- $0.00 / 1kg
-
2023-12-20
- CAS:56341-41-4
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1 ton
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| | 5-Fluoro-2-oxindole Basic information |
| | 5-Fluoro-2-oxindole Chemical Properties |
| Melting point | 143-147 °C (lit.) | | Boiling point | 307.2±42.0 °C(Predicted) | | density | 1.311±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 12.99±0.20(Predicted) | | form | Powder or Crystalline Powder | | color | White to pale brown | | InChIKey | DDIIYGHHUMKDGI-UHFFFAOYSA-N | | CAS DataBase Reference | 56341-41-4(CAS DataBase Reference) |
| | 5-Fluoro-2-oxindole Usage And Synthesis |
| Chemical Properties | Light Yellow Crystalline | | Uses | 5-Fluoro-2-oxindole (cas# 56341-41-4) is a compound useful in organic synthesis. | | Application | 5-Fluoro-2-oxindole is a ketone organic compound that can be used as an intermediate in the preparation of sunitinib. Sunitinib is a novel multi-targeted oral drug for the treatment of tumors. | | Preparation | synthesis of 5-fluoro-2-oxindole: 4-fluoroaniline was used as the starting material, reacted with chloral hydrate and hydroxylamine hydrochloride to generate 4-fluoroisonitrosoacetanilide, and then cyclized under the action of concentrated sulfuric acid to form the compound 5-fluoroisatin was finally obtained by wolff-kishner-huang minlon reduction to obtain 5-fluoro-2-oxindole with a total yield of 66%. |
| | 5-Fluoro-2-oxindole Preparation Products And Raw materials |
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