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| | (1S)-(+)-(Camphorylsulfonyl)oxaziridine Basic information |
| Product Name: | (1S)-(+)-(Camphorylsulfonyl)oxaziridine | | Synonyms: | (+)-(2R,8AS)-(CAMPHORYLSULFONYL)OXAZIRIDINE;(2R,8AS)-(+)-(CAMPHORYLSULFONYL)OXAZIRIDINE;(1S)-(+)-2,N-EPOXY-EXO-10,2-BORNANESULTAM;(IS)-(+)-(10-Camphorsulfonyl)oxaziridine;S-(10-Camphorsulfonyl)oxaziridine;(4aS,7R,8aS)-9,9-DiMethyltetrahydro-4H-4a,7-Methanobenzo[c][1,2]oxazireno[2,3-b]isothiazole 3,3-dioxide;(+)-(2R,8aS)-10-(CaMphorylsulfonyl)oxaziridine;(4aS,7R,8aS)-Tetrahydro-9,9-diMethyl-4H-4a,7-Methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-Dioxide | | CAS: | 104322-63-6 | | MF: | C10H15NO3S | | MW: | 229.3 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;pharmacetical;chiral;Asymmetric Synthesis;Bicyclic Monoterpenes;Biochemistry;Oxidation;Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;Terpenes | | Mol File: | 104322-63-6.mol |  |
| | (1S)-(+)-(Camphorylsulfonyl)oxaziridine Chemical Properties |
| Melting point | 172-174 °C(lit.) | | alpha | 45 º (c=2, chloroform) | | Boiling point | 317.6±25.0 °C(Predicted) | | density | 1.2486 (rough estimate) | | refractive index | 1.5060 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | pka | -11.75±0.40(Predicted) | | form | Crystals or Crystalline Powder | | color | White | | optical activity | [α]28/D +45°, c = 2 in chloroform | | BRN | 6274370 | | CAS DataBase Reference | 104322-63-6(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 10 | | HS Code | 29309090 |
| | (1S)-(+)-(Camphorylsulfonyl)oxaziridine Usage And Synthesis |
| Chemical Properties | (1S)-(+)-(Camphorylsulfonyl)oxaziridine is white crystall powder | | Uses | (1S)-(+)-(Camphorylsulfonyl)oxaziridine is a useful synthetic intermediate. Used for asymmetric hydroxylation | | Uses | (1S)-(+)-(10-Camphorsulfonyl)oxaziridine can be used:
- To convert prochiral ketone enolates into optically active α-hydroxy ketones via enantioselective asymmetric oxidation.
- In the synthesis of thymidine oligonucleotides connected through pyrophosphates.
- In the asymmetric synthesis of proton pump inhibitors like (R)-Rabeprazole sodium and (R)-Lansoprazole sodium from the corresponding DBU salt of prochiral sulfide.
- In the preparation of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides by oxidizing the corresponding phosphinoacetate.
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| | (1S)-(+)-(Camphorylsulfonyl)oxaziridine Preparation Products And Raw materials |
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