| Company Name: |
Spectrum Chemical Manufacturing Corp.
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| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Email: |
marketing_china@spectrumchemical.com |
| Products Intro: |
Product Name:Tetraisopropyl PyrophosphoraMide
CAS:513-00-8
Package:100MG Remarks:T2700
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| | ISO-OMPA Basic information |
| Product Name: | ISO-OMPA | | Synonyms: | ISO-OMPA;tetraisopropylpyrophosphamide;Diphosphoramide, N,N,N,N-tetrakis(1-methylethyl)-;iso-OMPA, Tetra(monoisopropyl)pyrophosphortetramide;Dipropyldiphosphoramide;DPDA;Oxybis[bis(isopropylamino)phosphine oxide];[bis(isopropylamino)phosphoryloxy-(isopropylamino)phosphoryl]-isopropyl-amine | | CAS: | 513-00-8 | | MF: | C12H32N4O3P2 | | MW: | 342.36 | | EINECS: | 208-149-5 | | Product Categories: | | | Mol File: | 513-00-8.mol |  |
| | ISO-OMPA Chemical Properties |
| | ISO-OMPA Usage And Synthesis |
| Uses | Tetraisopropyl pyrophosphoramide has been used:
- as a butyrylcholinesterase inhibitor to determine the proportions of butyrylcholinesterase (BChE) in cat and tiger plasma
- to inhibit wild-type BChE in acetylcholinesterase assay
- to selectively block the enzymatic activity of AChE
| | Definition | ChEBI: Diphosphoramide, N,N',N'',N'''-tetrakis(1-methylethyl)- is a phosphoramide. | | Biochem/physiol Actions | Selective inhibitor of butyrylcholinesterase | | in vivo | Iso-OMPA (0.6-1.9 mg/kg, subcutaneous injection, single dose) enhances soman toxicity in rats but has no effect on mice[3]. | Animal Model: | Mouse and rat[3] | | Dosage: | 0.6, 1.9 mg/kg; single dose | | Administration: | Subcutaneous injection (s.c.) | | Result: | Caused rat plasma CarbE activity to be only slightly inhibited by lower doses and significantly inhibited by higher doses. CarbE activity in mice was not inhibited. |
| | IC 50 | BuChE |
| | ISO-OMPA Preparation Products And Raw materials |
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