- corticosterone
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- $10.00 / 1kg
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2024-03-08
- CAS:56-47-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Deoxycorticosterone acetate
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- $15.00 / 1KG
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2021-07-13
- CAS:56-47-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Deoxycorticosterone acetate Basic information |
| | Deoxycorticosterone acetate Chemical Properties |
| Melting point | 157°C | | alpha | D20 +168 to +176° (dioxane) | | Boiling point | 421.94°C (rough estimate) | | density | 1.0415 (rough estimate) | | refractive index | 175 ° (C=1, Dioxane) | | storage temp. | Sealed in dry,Room Temperature | | solubility | H2O: insoluble | | color | White to Off-White | | Water Solubility | 4mg/L(25 ºC) | | Merck | 2901 | | BRN | 2570798 | | InChI | InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1 | | InChIKey | VPGRYOFKCNULNK-ACXQXYJUSA-N | | SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@H](C(=O)COC(C)=O)CC3)CC2 | | LogP | 3.080 | | CAS DataBase Reference | 56-47-3(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | RIDADR | UN 2811 | | WGK Germany | 3 | | RTECS | HG0525000 | | HazardClass | IRRITANT | | HS Code | 2937290000 |
| | Deoxycorticosterone acetate Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Adrenocortical/mineralocorticoid Steroid. | | Uses | Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats. | | Definition | ChEBI: Deoxycorticosterone acetate is a corticosteroid hormone. | | Brand name | Doca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.]. | | General Description | Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one. | | Purification Methods | 11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.] |
| | Deoxycorticosterone acetate Preparation Products And Raw materials |
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