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MS012

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MS012 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:MS012；MS-012;MS 012
CAS:2089617-83-2
Package:25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Email: marketing1@energy-chemical.com
Products Intro: Product Name:MS012 >=98% (HPLC)
CAS:2089617-83-2
Purity:NULL Package:1ea;25mg;5mg Remarks:NULL
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:MS012;MS012
CAS:2089617-83-2
Purity:98% Package:5 mg
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Email: cindy.huang@synzest.com
Products Intro: Product Name:MS012
CAS:2089617-83-2
Purity:98% Package:10mg 100mg
MS012 Basic information
Product Name:MS012
Synonyms:MS012;MS012 >=98% (HPLC);2,4-Quinazolinediamine, N2-hexyl-6,7-dimethoxy-N4-(1-methyl-4-piperidinyl)-
CAS:2089617-83-2
MF:C22H35N5O2
MW:401.55
EINECS:
Product Categories:
Mol File:2089617-83-2.mol
MS012 Structure
MS012 Chemical Properties
Boiling point 562.0±60.0 °C(Predicted)
density 1.137±0.06 g/cm3(Predicted)
pka8.66±0.10(Predicted)
Safety Information
MSDS Information
MS012 Usage And Synthesis
DescriptionMS012 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. MS012 exhibited stronger binding affinity to GLP (Kd = 46 ± 15 nM) than G9a (Kd = 610 ± 68 nM). MS012 was 13-fold selective for GLP over G9a. G9a-like protein (GLP) and G9a are highly homologous protein lysine methyltransferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains. GLP and G9a form a heterodimer complex and catalyze mono- and dimethylation of histone H3 lysine 9 and nonhistone substrates.
MS012 Preparation Products And Raw materials
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