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4-Fluorobenzyl bromide

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CAS:459-46-1
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CAS:459-46-1
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CAS:459-46-1
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4-Fluorobenzyl bromide manufacturers

  • 4-Fluorobenzyl bromide
  • $15.00-10.00 / KG
  • 2021-07-13
  • CAS:459-46-1
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • 4-Fluorobenzyl bromide
  • $2.00 / KG
  • 2020-01-08
  • CAS:459-46-1
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 100g , 1kg, 5kg , 50kg
  • 4-Fluorobenzyl bromide
  • $0.10 / KG
  • 2020-01-08
  • CAS:459-46-1
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 1000 tons
4-Fluorobenzyl bromide Basic information
Chemical Properties Uses
Product Name:4-Fluorobenzyl bromide
Synonyms:P-FLUOROBENZYL BROMIDE;4-Fluoro-1-(bromomethyl)benzene;α-Bromo-4-fluorotoluene;4-Fluorobenzyl bromi;BroMobenzene of fluoride;Of fluoride broMide;1-(Bromomethyl)-4-fluorobenzene, alpha-Bromo-4-fluorotoluene;α-BroMo-p-fluorotoluene
CAS:459-46-1
MF:C7H6BrF
MW:189.02
EINECS:207-291-5
Product Categories:Benzyl;Fluoro-contained benzyl bromide series;Fluorinated benzene series;alkyl bromide|alkyl Fluorine;Halogenated Heterocycles ,Pyrimidines
Mol File:459-46-1.mol
4-Fluorobenzyl bromide Structure
4-Fluorobenzyl bromide Chemical Properties
Boiling point 85 °C15 mm Hg(lit.)
density 1.517 g/mL at 25 °C(lit.)
refractive index n20/D 1.547(lit.)
Fp >230 °F
storage temp. Inert atmosphere,2-8°C
form Liquid
Specific Gravity1.517
color Clear colorless to yellow
Sensitive Lachrymatory
BRN 636507
InChIKeyNVNPLEPBDPJYRZ-UHFFFAOYSA-N
CAS DataBase Reference459-46-1(CAS DataBase Reference)
NIST Chemistry Reference«alpha»-Bromo-4-fluorotoluene(459-46-1)
EPA Substance Registry System4-Fluorobenzyl bromide (459-46-1)
Safety Information
Hazard Codes C
Risk Statements 34-36
Safety Statements 26-36/37/39-45
RIDADR UN 3265 8/PG 2
WGK Germany 3
Hazard Note Corrosive/Lachrymatory
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29039990
MSDS Information
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4-Fluorobenzyl bromide English
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4-Fluorobenzyl bromide Usage And Synthesis
Chemical Properties

4-Fluorobenzyl bromide (C7H6BrF, CAS registry No. 459-46-1) is a colorless to light yellow liquid. Its flash point is 74.8 oC. It is stable at room temperature in closed containers under normal storage and handling conditions. 1,3-Difluorobenzene can react with water to form toxic fumes. Therefore, it should be stored in a tightly closed container and should be stored in a cool, dry and well-ventilated area away from incompatible substances.

Uses

4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.
4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.

Chemical PropertiesColorless to light yellow liqui
Uses4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.
4-Fluorobenzyl bromide Preparation Products And Raw materials
Preparation Products4-Fluorobenzyl alcohol-->2-IODOBENZAMIDE-->(4-FLUORO-BENZYL)-METHYL-AMINE
Tag:4-Fluorobenzyl bromide(459-46-1) Related Product Information
9-BROMO-2-NITROFLUORENE ALPHA-METHYL-2-TRIFLUOROMETHYLBENZYL BROMIDE ALPHA,ALPHA,ALPHA',ALPHA'-TETRABROMO-O-XYLENE O-BROMOMETHYLBENZOYL BROMIDE 2,4-Bis(trifluoromethyl)benzyl bromide 3-Bromophthalide 1,2-Bis(bromomethyl)benzene 9-BROMOFLUORENE 2-(Trifluoromethyl)benzyl bromide 1,2,4,5-TETRAKIS(BROMOMETHYL)BENZENE 1-BROMOMETHYL-2-[(PHENYLSULFONYL)METHYL]BENZENE 4-Fluorobenzyl bromide [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-pro p-1-enyl-cyclopropane-1-carboxylate Ethyl bromodifluoroacetate 4-Fluorobenzyl chloride BRETYLIUM TOSYLATE alpha-Chloro-o-fluorotoluene Bromine