ChemicalBook > Product Catalog >Organic Chemistry >Hydrocarbons and derivatives >Hydrocarbon halides >4-Fluorobenzyl bromide

4-Fluorobenzyl bromide

4-Fluorobenzyl bromide Suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:4-Fluorobenzyl Bromide
CAS:459-46-1
Purity:99% Package:25KG
Company Name: Henan Fengda Chemical Co., Ltd
Tel: +86-371-86557731 +86-13613820652
Email: info@fdachem.com
Products Intro: Product Name:4-Fluorobenzyl bromide
CAS:459-46-1
Purity:99% Package:1KG;100USD|1000KG;1USD
Company Name: Frapp's ChemicalNFTZ Co., Ltd.
Tel: +86 (576) 8169-6106
Email: sales@frappschem.com
Products Intro: Product Name:4-Fluorobenzyl bromide
CAS:459-46-1
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Email: sales@capotchem.com
Products Intro: Product Name:4-Fluorobenzyl bromide
CAS:459-46-1
Purity:98%(Min,HPLC) Package:1G;1KG;100KG
Company Name: Hi-Tech Chemistry Corp
Tel: 0519-86626038
Email: yuhh@hitechem.com
Products Intro: Product Name:4-Fluorobenzyl bromide
CAS:459-46-1

4-Fluorobenzyl bromide manufacturers

  • 4-Fluorobenzyl bromide
  • 4-Fluorobenzyl bromide pictures
  • $100.00 / 1KG
  • 2023-12-26
  • CAS:459-46-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
  • 4-Fluorobenzyl Bromide
  • 4-Fluorobenzyl Bromide pictures
  • $0.00 / 25KG
  • 2023-07-28
  • CAS:459-46-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
4-Fluorobenzyl bromide Basic information
Chemical Properties Uses
Product Name:4-Fluorobenzyl bromide
Synonyms:α-Bromo-4-fluorotoluene;4-Fluorobenzyl bromi;BroMobenzene of fluoride;Of fluoride broMide;1-(Bromomethyl)-4-fluorobenzene, alpha-Bromo-4-fluorotoluene;α-BroMo-p-fluorotoluene;Toluene, α-broMo-p-fluoro- (6CI,7CI,8CI);The fluorine broMine benzyl
CAS:459-46-1
MF:C7H6BrF
MW:189.02
EINECS:207-291-5
Product Categories:Benzyl;Fluoro-contained benzyl bromide series;alkyl bromide|alkyl Fluorine;Halogenated Heterocycles ,Pyrimidines;Fluorinated benzene series;bc0001
Mol File:459-46-1.mol
4-Fluorobenzyl bromide Structure
4-Fluorobenzyl bromide Chemical Properties
Boiling point 85 °C15 mm Hg(lit.)
density 1.517 g/mL at 25 °C(lit.)
refractive index n20/D 1.547(lit.)
Fp >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility soluble in Chloroform
form Liquid
Specific Gravity1.517
color Clear colorless to yellow
Sensitive Lachrymatory
BRN 636507
InChIKeyNVNPLEPBDPJYRZ-UHFFFAOYSA-N
CAS DataBase Reference459-46-1(CAS DataBase Reference)
NIST Chemistry Reference«alpha»-Bromo-4-fluorotoluene(459-46-1)
EPA Substance Registry System4-Fluorobenzyl bromide (459-46-1)
Safety Information
Hazard Codes C
Risk Statements 34-36
Safety Statements 26-36/37/39-45
RIDADR UN 3265 8/PG 2
WGK Germany 3
Hazard Note Corrosive/Lachrymatory
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29039990
MSDS Information
ProviderLanguage
4-Fluorobenzyl bromide English
SigmaAldrich English
ACROS English
ALFA English
4-Fluorobenzyl bromide Usage And Synthesis
Chemical Properties

4-Fluorobenzyl bromide (C7H6BrF, CAS registry No. 459-46-1) is a colorless to light yellow liquid. Its flash point is 74.8 oC. It is stable at room temperature in closed containers under normal storage and handling conditions. 1,3-Difluorobenzene can react with water to form toxic fumes. Therefore, it should be stored in a tightly closed container and should be stored in a cool, dry and well-ventilated area away from incompatible substances.

Uses

4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.
4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.

Chemical PropertiesColorless to light yellow liqui
Uses4-Fluorobenzyl bromide was used in the preparation of:
  • 3-acetyl-1-(4-fluorobenzyl)-4-hydroxy-1H-indole
  • 1-(4-fluorobenzyl)-5-(pyrrolidine-1-sulfonyl)isatin
  • (S)-1-(4-fluorobenzyl)-5-(2-(4-fluorophenoxymethyl)pyrrolidine-1-sulfonyl)isatin
  • 8-bromo 9-(4-fluorobenzyl) adenine
  • 8-bromo 3-(4-fluorobenzyl) adenine
Uses4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials.
Tag:4-Fluorobenzyl bromide(459-46-1) Related Product Information
Rocuronium bromide [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl 2,2-dimethyl-3-pro p-1-enyl-cyclopropane-1-carboxylate Diethylstilbestrol Ethyl bromodifluoroacetate Fluorobenzene Ethidium bromide 4-Fluorobenzyl chloride BRETYLIUM TOSYLATE Allyl bromide Sodium bromate alpha-Chloro-o-fluorotoluene 4-n-Propoxyphenylacetylene Bromine 1,2-Bis(bromomethyl)benzene 9-BROMOFLUORENE 2-(Trifluoromethyl)benzyl bromide 1,2,4,5-TETRAKIS(BROMOMETHYL)BENZENE Methyl bromide