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| | 3,4,5-TRICHLOROTHIOPHENE-2-CARBONYL CHLORIDE Basic information |
| Product Name: | 3,4,5-TRICHLOROTHIOPHENE-2-CARBONYL CHLORIDE | | Synonyms: | 3,4,5-TRICHLOROTHIOPHENE-2-CARBONYL CHLORIDE;3,4,5-Trichlorothien-2-carboxylic acid chloride;3,4,5-trichloro-2-thiophenecarbonyl chloride;2-Thiophenecarbonyl chloride, 3,4,5-trichloro-;Rivaroxaban Impurity 166;trichlorothiophene-2-carbonyl chloride | | CAS: | 24422-15-9 | | MF: | C5Cl4OS | | MW: | 249.93 | | EINECS: | 000-000-0 | | Product Categories: | | | Mol File: | 24422-15-9.mol |  |
| | 3,4,5-TRICHLOROTHIOPHENE-2-CARBONYL CHLORIDE Chemical Properties |
| Melting point | 38-40°C | | Boiling point | 124-125°C 10mm | | Fp | 124-125°C/10mm | | Sensitive | Moisture Sensitive | | BRN | 1427060 |
| Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | 3261 | | HazardClass | 8 | | PackingGroup | II |
| Provider | Language |
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ALFA
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| | 3,4,5-TRICHLOROTHIOPHENE-2-CARBONYL CHLORIDE Usage And Synthesis |
| Preparation | 3,4,5-Trichlorothiophene-2-carbonyl chloride synthesis: A mixture of 3,4,5-trichloro-2-thiophenecarboxylic acid (20.4 g, 0.088 mol), SOCl2 (7.3 mL, 0.1 mol), and DMF (0.2 mL) in 80 mL of 1,2-dichloroethane was heated at reflux temperature for 3 h. The reaction mixture became homogeneous after 1 h of heating. The solution was cooled to 25℃, concentrated and placed under high vacuum to remove residual solvent, giving 22.0 g (98% wt.) of 3,4,5-trichloro-2-thiophenecarbonyl chloride as an oil which solidified on standing to an off-white powder; m.p. 37-41℃, having a GC area % purity > 99%. |
| | 3,4,5-TRICHLOROTHIOPHENE-2-CARBONYL CHLORIDE Preparation Products And Raw materials |
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