| Company Name: |
Shanghai Chaolan Chemical Technology Center
|
| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:CC618
CAS:1680204-90-3
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
|
| Company Name: |
Shanghai Dongyang Biotechnology Co., Ltd.
|
| Tel: |
0512-0512-13601744364 13601744364 |
| Email: |
chemsharker@126.com |
| Products Intro: |
Product Name:CC618
CAS:1680204-90-3
Purity:98% Package:1g 5g 10g 25g 50g 100g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:CC618;CC618,CC-618
CAS:1680204-90-3
Purity:99.37% Package:1 mg;10 mg;100 mg;200 mg;25 mg;5 mg;50 mg
|
|
| Product Name: | CC-618 | | Synonyms: | CC-618;5-Thiazolecarboxamide, 4-methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-;CC618,CC-618 | | CAS: | 1680204-90-3 | | MF: | C20H15F6N3O3S2 | | MW: | 523.47 | | EINECS: | | | Product Categories: | | | Mol File: | 1680204-90-3.mol |  |
| | CC-618 Chemical Properties |
| density | 1.466±0.06 g/cm3(Predicted) | | pka | 9.39±0.46(Predicted) |
| | CC-618 Usage And Synthesis |
| Description | CC618 is a potent and selective PPARβ/δ antagonist. CC618 selectively antagonizes agonist-induced PPARβ/δ activity with an IC50 = 10.0 μM. The treatment of PPARβ/δ with CC618 leads to a covalent modification of Cys249, located centrally in the PPARβ/δ ligand binding pocket, corresponding to the conversion of its thiol moiety to a 5-trifluoromethyl-2-pyridylthioether. |
| | CC-618 Preparation Products And Raw materials |
|